Confocal scanning and optical coherence tomograph based on self-adaptive optical technology

Abstract

A confocal scanning and optical coherence tomograph based on self-adaptive optical technology comprises a light source component, a scanning and lighting light path component, an aberration detection and correction component, a confocal imaging detection component, a reference arm component and an optical coherence tomography detection component, wherein the components are linked by optical fiber and / or spherical reflecting telescopes; one part of low-coherent light emitted by the light source component enters into the reference arm component and then returns along the original path and the other part enters into the samples to be detected through the aberration detection and correction component and the scanning and lighting light path component in sequence and then returns from the samples to be detected along the original path; one part of the returning light is reflected to the aberration detection and correction component by a spectroscope and the other part is transmitted to another spectroscope and then is split into two parts, one part enters into the confocal imaging detection component and the other part enters into the optical coherence tomography detection component after being coupled with the light returning from the reference arm component. The tomograph can realize high-resolution three-dimensional imaging of the objects to be detected.

Description

technical field [0001] The invention relates to a biological and medical imaging instrument, in particular to a confocal scanning and optical coherence tomography imager based on adaptive optics technology, which can realize three-dimensional high-resolution imaging of the human eye fundus (or other biological tissues). Background technique [0002] Confocal microscope technology was first used in biological tissue imaging, and developed into a mature laser confocal scanning imaging equipment in 1987. [0003] The invention patent No. US4863226 proposes the concept of Scanning Laser Ophthalmoscope (SLO), which realizes the horizontal scanning of the sample through the acousto-optic modulator, and realizes the longitudinal scanning of the sample through another scanning mirror. Scanning is frame scanning, and it is proposed to use pinholes to achieve confocal high-resolution imaging, but this invention patent only provides the principle device of confocal scanning imaging, an...

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Problems solved by technology

Invention patents with patent numbers ZL200610052463.8 and ZL200510012234.9 also proposed the principle device of optical coherence tomography, but the focus is on how to improve the focal depth of optical coherence tomography (OCT) and change the scanning mode, while High-resolution confocal images of the fundus (or the sample to be tested) cannot be obtained at the same time

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