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Dual component oral care product

A two-component, composition technology, applied in oral care, medical preparations containing active ingredients, drug combinations, etc.

Active Publication Date: 2011-01-05
COLGATE PALMOLIVE CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] Although the prior art discloses the use of various oral compositions in the treatment of dentine hypersensitivity, caries and enamel demineralization, there remains a need for other compositions and methods that provide improved performance in such treatments

Method used

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  • Dual component oral care product

Examples

Experimental program
Comparison scheme
Effect test

Embodiment I

[0069] A two-component (Component A and B) desensitizing dentifrice of the present invention, referred to as "Dentifrice X", Component A and Component B, was prepared. When combined in equal amounts for brushing teeth, Dentifrice X will effectively provide enhanced decay protection and remineralization properties. The ingredients of Part A and Part B are listed in Table I below.

[0070] Table 1

[0071]

[0072] In preparing dentifrice X, prepare Part A and Part B in which the glycerin, polyethylene glycol and organic thickener are dispersed in a conventional mixer until the mixture becomes a slurry which is smooth in appearance . Color and sweetener are dispersed in the slurry, after which water is added. L-arginine was then dispersed in the slurry and neutralized by adding phosphoric acid. Potassium nitrate was also added. After these components are mixed, the silica, dicalcium phosphate, and potassium sorbate components are then added to the individual components,...

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PUM

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Abstract

A dental composition which, e.g., eliminates or substantially reduces the discomfort and pain associated with dentinal hypersensitivity and exhibits enhanced anticaries and remineralization benefits, which composition contains a first component containing a calcium source, a second component containing an anion source and at least one of the components containing a basic amino acid in free or salt form, and the first and second components being maintained separate from each other until dispensed and combined for application to teeth.

Description

[0001] This application claims the benefit of US Application Serial No. 61 / 027,422, filed February 8, 2008, the contents of which are incorporated herein by reference. technical field [0002] The present invention relates to two-component dentifrice formulations wherein the active components of the formulation are separated from each other prior to use. In one embodiment, the present invention relates to desensitizing dentifrice compositions which eliminate or reduce discomfort and pain associated with dentin hypersensitivity, and more particularly to desensitizing dental compositions comprising A basic amino acid and a calcium ion component as well as an anionic component, the dental composition exhibits unexpectedly enhanced anticavity and remineralization properties. Background technique [0003] Dentin hypersensitivity is defined as acute localized toothache in response to physical stimuli on the dentin surface, such as thermal (hot or cold) stimuli of exposed dentin, o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/19A61K8/44A61K8/20A61K8/24A61Q11/00
CPCA61Q11/00A61K2800/88A61K8/21A61K8/44A61P1/02
Inventor R·科利R·罗宾逊R·萨利文D·库明斯N·贾亚拉曼
Owner COLGATE PALMOLIVE CO