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Antilipemic and antioxidant activities of different extracts of hemiptelea and application in medicine

A technology for extracts and water extracts, which is applied in the field of preparation of total flavonoids and water extracts of Ulmus chinensis, and can solve the problems of no reports on pharmacological activity

Inactive Publication Date: 2011-01-12
包海鹰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the research on the total flavonoids and water extract of Ulmus chinensis and its pharmacological activity has not been reported so far.

Method used

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  • Antilipemic and antioxidant activities of different extracts of hemiptelea and application in medicine
  • Antilipemic and antioxidant activities of different extracts of hemiptelea and application in medicine
  • Antilipemic and antioxidant activities of different extracts of hemiptelea and application in medicine

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Embodiment Construction

[0088] The preparation of the total flavonoids of Ulmus chinensis: the young stems and leaves of Ulmus chinensis are dried in an oven at 45°C, crushed and passed through a 60-mesh sieve. Then add 3 times the amount of 95% ethanol to extract at 60°C for 6 hours, and repeat three times. Combine the extracts, concentrate the combined extracts to a certain volume, add water to form a suspension, sequentially extract with an equal amount of petroleum ether and n-hexane, evaporate the water layer to dryness after extraction, and obtain the ethanol extract. Dissolve and filter with 95% ethanol, recover the filtrate under reduced pressure and evaporate to dryness. The evaporated ethanol extract was dissolved in water and passed through a polyamide column. It was eluted sequentially with water, 40% ethanol and 95% ethanol. The above eluate was recovered under reduced pressure and evaporated to dryness. The 40% ethanol eluent is the prepared flavonoids.

[0089] Preparation of the w...

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PUM

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Abstract

The invention discloses a preparation method of hemiptelea general flavone and water extract, and discloses the following two activities: (1) the hemiptelea general flavone and the water extract have prevention and treatment functions to the hyperlipidaemia, and have functions of reducing the serum total cholesterol (TC) content and reducing the low-density lipoprotein cholesterol (LDL-C) content along with the prolonging of the drug dispensing time; and (2) the hemiptelea general flavones has functions of anti-oxidizing and eliminating hydroxyl radical. The invention is not only suitable for developing the new drugs and functional health care products for preventing and treating the aging, heart cerebrovascular disease, atherosclerosis, inflammation and diseases closely related to the radical, but also suitable for developing the new drugs and functional health care products for preventing and treating the hyperlipidaemia.

Description

Technical field: [0001] The invention discloses a preparation method of total flavonoids and water extract of eucalyptus, which is suitable for the development of new drug products. The present invention also discloses the following two pharmacological activities: (1) the total flavonoids and water extract of Ulmus chinensis have preventive and therapeutic effects on hyperlipidemia, and with the prolongation of the medication time, they can successively reduce the serum total cholesterol (TC) content , Lowering the effect of low-density lipoprotein cholesterol (LDL-C) content. (2) The total flavonoids of Ulmus japonicus have the functions of anti-oxidation and scavenging hydroxyl free radicals. It belongs to the extraction and preparation of active ingredients of traditional Chinese medicine and its application in the fields of medicine and health care products. Background technique: [0002] The thorny elm (Hemiptelea davidii) belongs to the endemic plant of the genus Hem...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P3/06A61P39/06A23L1/30A61K135/00A61K127/00A23L33/105
Inventor 包海鹰李岩石利春
Owner 包海鹰
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