Oral medicament for treating osteonecrosis of femoral head

A femoral head necrosis and drug technology, applied in the direction of drug combination, bone disease, medical formula, etc., can solve the problems of high cost, high risk, and failure to delay the development of osteonecrosis

Inactive Publication Date: 2011-02-02
陈守杰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In surgical treatment, such as drilling decompression, the effective rate can reach about 80%, but it is only suitable for patients before early collapse; although total hip replacement has the characteristics of wide indication range and good effect, it is risky , The cost is high, and this method is only used when the condition is serious and drug treatment is ineffective
Although there have been published literatures on the treatment of femoral head necrosis with traditional Chinese medicine, most of them can only relieve pain, and cannot delay the development of osteonecrosis and completely cure it.

Method used

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  • Oral medicament for treating osteonecrosis of femoral head

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0207] Example 1: (Water decoction)

[0208] Ingredients formula:

[0209] Chuanxiong 10g; Corydalis 15g; Safflower 10g;

[0210] Ground beetle 10g; Salvia miltiorrhiza 20g; Caulis spatholobi 20g;

[0211] Angelica 15g; White Peony 15g; Astragalus 30g;

[0212] Codonopsis 12g; Shouwu 15g; Eucommia charcoal 15g;

[0213] Dipsacus 15g; Morinda officinalis 12g; Sichuan Achyranthes bidentata 15g;

[0214] Lycium barbarum 15g; Schisandra 12g; Drynaria fortunei 18g;

[0215] Atractylodes macrocephala 10g; Poria cocos 12g; Atractylodes macrocephala 10g;

[0216] Mulberry 18g; Papaya 15g; Fangji 12g;

[0217] Gentiana 15g; Qianjianjian 9g; Sea Tongpi 15g;

[0218] Fangfeng 10g; Guizhi 10g; Chuanwu 9g;

[0219] Caowu 9g; Cangzhu 12g; Earthworm 12g;

[0220] Gastrodia 15g; Oyster 20g; Alisma orientalis 10g;

[0221] Smilax glabra 20g; Licorice 9g.

[0222] Steps:

[0223] (1) Screen out each drug substance according to the ratio of each raw material, and reserve it after removing impurities;

[0224] (2) Add...

Embodiment 2

[0225] Example 2: (granules)

[0226] Ingredients formula:

[0227] Chuanxiong 9g; Corydalis 18g; Safflower 9g;

[0228] Ground turtle 9g; Salvia miltiorrhiza 21g; Caulis spatholobi 21g;

[0229] Angelica 17g; White Peony 14g; Astragalus 26g;

[0230] Codonopsis 11g; Shouwu 14g; Eucommia charcoal 13g;

[0231] Dipsacus 13g; Morinda officinalis 14g; Sichuan Achyranthes bidentata 13g;

[0232] Chinese wolfberry 13g; Schisandra 11g; Drynaria fortunei 16g;

[0233] Atractylodes macrocephala 9g; Poria cocos 14g; Alone living 9g;

[0234] Mulberry parasitic 16g; Papaya 17g; Fangji 14g;

[0235] Gentiana 10g; Qianjianjian 7g; Sea Tongpi 13g;

[0236] Fangfeng 9g; Guizhi 9g; Chuanwu 7g;

[0237] Caowu 7g; Cangzhu 11g; Earthworm 14g;

[0238] Gastrodia 13g; oyster 21g; Alisma 9g;

[0239] Smilax glabra 25g; Licorice 8g.

[0240] Steps:

[0241] (1) Screen out each drug substance according to the ratio of each raw material, and reserve it after removing impurities;

[0242] (2) After mixing the ingredients, ...

Embodiment 3

[0244] Example 3: (tablets)

[0245] Ingredients formula:

[0246] Chuanxiong 11g; Corydalis 13g; Safflower 11g;

[0247] Ground turtle 11g; Salvia miltiorrhiza 19g; Caulis spatholobi 19g;

[0248] Angelica 13g; White Peony 11g; Astragalus 33g;

[0249] Codonopsis 18g; Shouwu 11g; Eucommia charcoal 18g;

[0250] Dipsacus 18g; Morinda officinalis 11g; Sichuan Achyranthes bidentata 18g;

[0251] Chinese wolfberry 18g; Schisandra 9g; Drynaria fortunei 17g;

[0252] Atractylodes macrocephala 11g; Poria cocos 10g; Alone living 11g;

[0253] Mulberry 13g; Papaya 13g; Fangji 10g;

[0254] Gentiana 17g; Qianjianjian 8g; Sea Tongpi 18g;

[0255] Fangfeng 11g; Guizhi 11g; Chuanwu 11g;

[0256] Caowu 11g; Cangzhu 10g; Earthworm 10g;

[0257] Gastrodia 18g; Oyster 19g; Alisma orientalis 11g;

[0258] Smilax glabra 28g; Licorice 11g.

[0259] Steps:

[0260] (4) Screen out each drug substance according to the ratio of each raw material, and use it after removing impurities;

[0261] (5) After mixing the ingredi...

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Abstract

The invention discloses an oral medicament for treating osteonecrosis of the femoral head, which is mainly prepared from the following materials according to a certain weight ratio: szechuan lovage rhizome, rhizoma corydalis, red flower, Chinese polyphaga, salvia miltiorrhiza, suberect spatholobus stem, Chinese angelica, white paeony root, astragalus, codonopsis pilosula, prepared tuber of multiflower knotweed, eucommia ulmoides oliver, himalayan teasel root, medicinal indianmulberry root, medicinal cyathula root, medlar, Chinese magnoliavine fruit, fortune's drynaria rhizome, largehead atractylodes rhizome, indian buead, heracleum, Chinese taxillus twig, papaya, fangji root, root of largeleaf gentian, obscured homalomena rhizome, erythrina indica lam, divaricate saposhnikovia root, cassia twig, prepared common monkshood mother root, prepared kusnezoff monkshood root, swordlike atractylodes rhizome, earthworm, tall gastrodia tuber, oyster, oriental waterplantain rhizome, glabrous greenbrier rhizome and liquorice. The materials can be prepared into any common formulation for oral administration. The medicament for treating the osteonecrosis of the femoral head has the advantages of exact curative effect and high recovery rate by adopting treating means of traditional Chinese medicine according to the theory of traditional Chinese medicine and the non-surgical treatment principle of Western medicine.

Description

Technical field [0001] The invention relates to an oral medicine for treating femoral head necrosis and belongs to the field of traditional Chinese medicine. Background technique [0002] Femoral head necrosis, also known as avascular necrosis of the femoral head, is called osteoarthritis or bone atrophy in Chinese medicine. Most of them are caused by trauma, drugs (mainly long-term heavy use of hormonal drugs), alcohol stimulation (mainly long-term heavy drinking), rheumatism, blood disease, diving sickness, burns and other diseases. In short, various reasons destroy the blood supply of the femoral head , Which in turn causes necrosis. If the treatment is not timely, it can lead to lifelong disability. [0003] The prior art treatments for femoral head necrosis mainly include surgical treatment and non-surgical treatment. In surgical treatment, such as the drilling decompression method, the effective rate can reach about 80%, but it is only suitable for patients before the earl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P19/08A61K35/64A61K35/56A61K36/8988A61K35/618A61K35/62
Inventor 陈守杰
Owner 陈守杰
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