Device for monitoring nerve stimulation and response and system thereof as well as manufacturing method of device
A nerve stimulation and response technology, used in applications, medical science, artificial respiration, etc., can solve the problems of fragile, untestable organism design and placement, and high manufacturing costs
Inactive Publication Date: 2011-02-02
CHUNG HUA UNIVERSITY
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Problems solved by technology
[0002] Traditional microarray biological probes for biological nerve stimulation and response monitoring are fabricated on hard silicon wafer substrates. Such microarray biological probes are not only heavy and fragile, but also require high-temperature processes for fabrication, and the manufacturing cost is also very high. high
Furthermore, traditional microarray bioprobes cannot be designed and placed according to the outline of the organism to be tested, which affects the contact effect between the bioprobe and the object to be tested.
[0003] In addition, traditional microarray biological probes made of hard silicon wafer substrates need to be equipped with additional devices to process the signal-to-noise ratio and impedance matching of the extracted signals.
Therefore, conventional microarray bioprobes require a lot of cost and high complexity in production
[0004] In addition, traditional microarray-type biological probes are usually integrated with thin-film transistor amplifiers for signal processing. Although this integration can improve performance such as signal-to-noise ratio and impedance matching, the production of thin-film transistor amplifiers requires additional processes, so the cost is high and not easy to make
[0005] As far as the existing microarray bioprobe technology is concerned, there is still a lack of a method that can be easily manufactured in large quantities, has low cost, can be designed and placed according to the outline of the organism to be measured, and can simultaneously improve the signal-to-noise ratio and impedance. Microarray-type biological probe device with matching performance
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[0027] figure 1 A schematic diagram showing a neural stimulation and response monitoring system according to an embodiment of the present invention. The nerve stimulation and response monitoring system 100 includes a probe device 102 , a transceiver device 104 and a host 106 . The probe device 102 includes an antenna 118 , a modulation and demodulation module 120 , a rectification module 110 , a resistor-capacitor circuit 112 , a single chip system unit 114 and a plurality of biological probes 116 , wherein the probe device 102 is built on a flexible substrate. In an embodiment, the modulation and demodulation module 120 , the rectification module 110 , and the system-on-a-chip unit 114 can be integrated in the chip 108 . The antenna 118 can be formed on the flexible substrate, and the modulation and demodulation module 120 is arranged on the flexible substrate, and it is used for demodulating the nerve stimulation microwave coded signal sent from the transceiver device 104, ...
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The invention relates to a device for monitoring nerve stimulation and response and a system thereof as well as a manufacturing method of the device. A probe device for monitoring nerve stimulation and response is connected with a host and comprises a flexible substrate, a modulating and demodulating module, a single chip system unit and a plurality of biological probes. The modulating and demodulating module and single chip system unit can be encapsulated on the flexible substrate after being integrated, and the modulating and demodulating module is used for demodulation receiving or modulation transmitting of microwave coded signal. The single chip system unit decodes the microwave coded signal and acquires an electric nerve stimulation driving signal by virtue of conversion process. The biological probe is convexly arranged on the flexible substrate and is coupled with the single chip system unit. The biological probe is used for transmitting the electric stimulation driving signalto epidermis nerve or receiving a nerve response signal by virtue of the single chip system unit, amplification, analysis, classification and encoding are carried out, and then the signal is transmitted to an antenna by virtue of the modulating and demodulating module, so that the signal is sent back to the host to be monitored and analyzed.
Description
technical field [0001] The present invention relates to a device and system for nerve stimulation and response monitoring, specifically to a device and system for nerve stimulation and response monitoring made using wireless identification tag technology and low temperature technology and flexible substrate. Background technique [0002] Traditional microarray biological probes for biological nerve stimulation and response monitoring are fabricated on hard silicon wafer substrates. Such microarray biological probes are not only heavy and fragile, but also require high-temperature processes for fabrication, and the manufacturing cost is also very high. high. Furthermore, traditional microarray bioprobes cannot be designed and placed according to the outline of the organism to be tested, which affects the contact effect between the bioprobe and the object to be tested. [0003] In addition, traditional microarray biological probes made of hard silicon wafer substrates need to...
Claims
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IPC IPC(8): A61N1/36A61B5/00
Inventor 林君明翁秀美林伯威潘力诚
Owner CHUNG HUA UNIVERSITY