Medicinal preparation for treating primary dysmenorrhea and preparation method thereof

A technology for primary dysmenorrhea and pharmaceutical preparations, applied in the direction of non-central analgesics, drug combinations, pharmaceutical formulations, etc., can solve the problem that primary dysmenorrhea cannot be fundamentally treated, and achieve stable and feasible preparation process and mild effect , use the effect of safety

Active Publication Date: 2011-02-16
GUIZHOU BAILING GRP PARMACEUTIAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are also traditional Chinese medicines with mild properties and less toxic side effects, such as Yueyueshu Oral Liquid, Wuji Baifeng Pills, etc., to relieve abdominal pain. Although these traditional Chinese medicines have certain curative effects, they still need to be taken in time to avoid dysmenorrhea every time they menstruate. , unable to fundamentally treat primary dysmenorrhea

Method used

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  • Medicinal preparation for treating primary dysmenorrhea and preparation method thereof
  • Medicinal preparation for treating primary dysmenorrhea and preparation method thereof
  • Medicinal preparation for treating primary dysmenorrhea and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Example 1: Weigh 20g of Rhizoma Cyperi, 10g of Artemisia argyi, 60g of Astragalus, 100g of Angelica, 80g of Motherwort, 80g of Xuanhu, 100g of Rehmannia glutinosa, 100g of red dates and 20g of ginger, add 4.6kg of water to soak for 2 hours, decoct for 2 hours times, 1.5 hours each time, filter;

[0057] ②Combine the filtrates, concentrate the filtrates to 1 / 3 of the original liquid, add 500g brown sugar and heat to dissolve, then concentrate to a thick paste with a relative density of 1.20-1.24 measured at 80-85°C, and bottle it to obtain the ointment. The preparation is taken orally, once a day, 10g each time, and one to two months is a course of treatment.

Embodiment 2

[0058] Example 2: ① Weigh 10g Cyperus cyperi, 5g Artemisia argyi, 30g Astragalus, 50g Angelica, 80g Motherwort, 100g Xuanhu, 150g Rehmannia glutinosa, 150g red dates and 40g ginger, add 5.5kg of water to soak for 2 hours, decoct 3 times, 2 hours each time, filter;

[0059] ② Combine the filtrates and concentrate the filtrates to a thick paste with a relative density of 1.20-1.24 measured at 80-85°C;

[0060] ③ Add sucrose and microcrystalline cellulose, mix evenly, dry under reduced pressure at 60°C, pulverize, sieve, mix evenly, size the granules, and pack separately to obtain granules. The preparation is taken with boiled water, once a day, 10g each time, and one to two months is a course of treatment.

Embodiment 3

[0061] Example 3: ①Weigh 40g Cyperus cyperi, 20g mugwort leaves, 90g astragalus, 150g angelica, 50g motherwort, 75g Xuanhu, 50g rehmannia glutinosa, 50g red dates and 10g ginger, add 3.2kg water to soak for 2 hours, decoct for 2 hours times, 1.5 hours each time, filter;

[0062] ② Combine the filtrates and concentrate the filtrates to a thick paste with a relative density of 1.20-1.24 measured at 80-85°C;

[0063] ③ Add starch and microcrystalline cellulose, mix well, dry under reduced pressure at 60°C, pulverize, sieve, mix well, granulate, add magnesium stearate, and then press the granules into tablets with a punching device to obtain tablets agent. The preparation is taken orally, once a day, 3 tablets each time, and one to two months is a course of treatment.

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Abstract

The invention discloses a medicinal preparation for treating primary dysmenorrhea and a preparation method thereof. The medicinal preparation comprises the following raw materials in part by weight: 1 to 4 parts of nutgrass galingale rhizome, 0.5 to 2 parts of Chinese mugwort leaf, 3 to 9 parts of astragalus, 5 to 15 parts of Chinese angelica, 5 to 10 parts of motherwort herb, 5 to 10 parts of yanhusuo, 5 to 15 parts of prepared rehmannia root, 5 to 15 parts of red jujube and 1 to 4 parts of ginger. The preparation method comprises the following steps of: immersing the raw materials into water in an amount which is 6 to 10 times that of the raw materials for 2 hours, decocting the mixture for 1 to 3 times and 1 to 2 hours each time, filtering and merging filter liquor; concentrating the filter liquor to form thick paste with the measured relative density of between 1.20 and 1.24 at the temperature of between 80 and 85 DEG C, or concentrating the filter liquor until the filter liquor is 1/3 of the original liquid volume, adding a proper amount of brown sugar, dissolving the brown sugar through heating, concentrating the mixture to form thick paste with the measured relative density of between 1.20 and 1.24 at the temperature of between 80 and 85 DEG C, and preparing a preparation. Clinical experiments prove that the medicinal preparation has the effects of promoting blood circulation and removing blood stasis, warming channels and invigorating pulse and promoting qi circulation and relieving pain and good treatment effect, can be used for treating the primary dysmenorrhea, has unique curative effect, is safe to use and does not have any toxic or side effect.

Description

technical field [0001] The invention relates to a medicinal preparation and a preparation method for treating dysmenorrhea, in particular to a medicinal preparation and a preparation method for treating primary dysmenorrhea. Background technique [0002] Dysmenorrhea refers to periodic lower abdominal pain during menstruation in mature women, which can be divided into secondary dysmenorrhea and primary dysmenorrhea. Primary dysmenorrhea is more common in young women, and often occurs with menarche and endocrine disorders. The National Women's Menstrual Physiological Constant Cooperative Group conducted a survey and analysis of more than 130,000 women's menstrual physiological constants in 29 provinces, municipalities, and autonomous regions across the country. In my country, 33.19% of women have menstrual dysmenorrhea, 45.73% are mild, 38.81% are moderate, and 38.81% are severe. 13.55%. The incidence of dysmenorrhea is on the rise every year at home and abroad, and dysmenor...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K36/9068A61P29/02A61P15/00A61K9/16A61K9/06A61K9/20
Inventor 夏文肖锦新安斯扬蒋坤
Owner GUIZHOU BAILING GRP PARMACEUTIAL CO LTD
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