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Traditional Chinese medicine composition for treating lung cancer, preparation method and application thereof

A composition and lung cancer technology, which can be applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., and can solve the problem of low anti-cancer effect

Inactive Publication Date: 2011-03-02
JIANGSU PROVINCIAL HOSPITAL OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In my country, traditional Chinese medicine preparations are very common in the treatment of malignant tumors, but there are not many drugs that have been confirmed by modern medicine to have positive anti-cancer effects, and even fewer of them have anti-cancer effects comparable to chemotherapy drugs

Method used

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  • Traditional Chinese medicine composition for treating lung cancer, preparation method and application thereof
  • Traditional Chinese medicine composition for treating lung cancer, preparation method and application thereof
  • Traditional Chinese medicine composition for treating lung cancer, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A compound combination medicine for treating lung cancer, comprising the following components in parts by weight: 10 parts of astragalus, 5 parts of mylabris, 10 parts of gecko, 10 parts of mountain bean root, 10 parts of leech, 10 parts of curcuma, and 10 parts of ground beetle.

[0022] Weigh the above Qiwei herbs in parts by weight, add 5 times the water to soak for 60 minutes, decoct 3 times, 2 hours each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.05g / mL (60°C ) extract, add ethanol until the alcohol content is 70% (v / v), let it stand for 24 hours, take the supernatant, recover the ethanol until it has no alcohol smell and concentrate to an appropriate amount, add water to 5000mL, stir well, and pack , sterilized by circulating steam for 35 minutes to obtain the mixture.

Embodiment 2

[0024] A compound combination medicine for treating lung cancer, comprising the following components in parts by weight: 10 parts of astragalus, 8 parts of mylabris, 30 parts of gecko, 20 parts of mountain bean root, 10 parts of leech, 20 parts of curcuma, and 20 parts of ground beetle.

[0025] Weigh the above Qiwei herbs in parts by weight, add 8 times the weight of water to soak for 30 minutes, decoct for 3 hours, filter, and concentrate the filtrate under reduced pressure to an extract with a relative density of 1.15g / mL (60°C), add ethanol to The alcohol content is 80% (v / v), let it stand for 24 hours, take the supernatant, recover the ethanol until it has no alcohol smell and continue to concentrate to a relative density of about 1.20g / ml (measured at 80°C), vacuum dry, and granulate , Tablets, that is, tablets.

Embodiment 3

[0027] A compound combination medicine for treating lung cancer, comprising the following components in parts by weight: 10 parts of astragalus, 6 parts of mylabris, 30 parts of gecko, 15 parts of mountain bean root, 13 parts of leech, 30 parts of curcuma, and 30 parts of ground beetle.

[0028] Weigh the above seven herbs according to parts by weight, add 15 times the weight of water to soak for 45 minutes, decoct twice for 1 hour each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.10g / mL (60°C ) extract, add ethanol until the alcohol content is 60% (v / v), let it stand for 24 hours, take the supernatant, reclaim the ethanol until it has no alcohol smell and concentrate to a relative density of about 1.20g / ml (measured at 80°C ), vacuum-dried, granulated, and packed into capsules to obtain capsules.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating lung cancer, which comprises the following components in parts by weight: 10-20 parts of radix astragali, 5-8 parts of blister beetle, 10-30 parts of wall lizard, 10-30 parts of vietnamese sophora root, 10-30 parts of leech, 10-30 parts of zedoary and 10-30 parts of ground beetle. The invention also discloses a preparation method of the traditional Chinese medicine composition and application thereof to preparing a medicine for treating lung cancer. The traditional Chinese medicine composition for treating the lung cancer has the advantages that the blister beetle, the wall lizard and the vietnamese sophora root have the efficacy of relieving diseases, dissipating stagnation, eliminating toxin and resisting cancer; the leech, the zedoary and the ground beetle have the efficacy of invigorating blood circulation to dispel blood stagnation, and relieving stagnation to dredge channels; the radix astragali is mainly utilized for tonifying qi and strengthening body resistance to eliminate pathogen without hurting health; and combination of the components exerts the efficacy of relieving toxin, resisting cancer, softening hardness to dissipate stagnation, invigorating blood circulation to dispel blood stagnation, tonifying qi and strengthening body resistance. In addition, clinical and experimental research shows that the composition has obvious inhibitory action on lung cancer cells.

Description

technical field [0001] The invention relates to a Chinese medicine compound and its preparation method and application, in particular to a Chinese medicine composition for treating lung cancer and its preparation method and application. Background technique [0002] With the aggravation of the natural population growth and population aging process in our country, the development and death of lung cancer will rank first among the malignant tumors in our country for quite some time. Although the survival rate and quality of life of advanced lung cancer, which are clinically difficult, have been improved to a certain extent, they are still unsatisfactory. There are many reports on the treatment of non-small cell lung cancer with traditional Chinese medicine, and its prospects have attracted much attention. The combination of traditional Chinese medicine with surgery, radiotherapy, and chemotherapy can effectively prolong the survival period and improve the quality of life in th...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P35/00A61P11/00A61K35/64A61K35/56A61K35/62A61K35/583
Inventor 王居祥王瑞平邹玺刘志辉朱超林胡玥
Owner JIANGSU PROVINCIAL HOSPITAL OF TCM