Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Quality control method for infantile cough syrup as Chinese medicine preparation

A quality control method and a technology for relieving cough in children, which are applied in directions such as pharmaceutical formulations, measuring devices, and drug combinations, can solve problems such as imperfect identification items and identification methods, and achieve the effects of perfecting quality standards and improving quality control.

Active Publication Date: 2011-05-25
津药达仁堂集团股份有限公司乐仁堂制药厂
View PDF1 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] But do not see as yet identical with the Ministry of Health standard WS3-B-2832-98 infant cough syrup prescription of above-mentioned disclosure, proportioning is identical, the improved document of the product standard of identical effect, also exists identification project, identification in the standard of prior art In order to improve the product quality of traditional Chinese medicine, it is necessary to improve the product quality standard

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Quality control method for infantile cough syrup as Chinese medicine preparation
  • Quality control method for infantile cough syrup as Chinese medicine preparation
  • Quality control method for infantile cough syrup as Chinese medicine preparation

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0052] Preparation of reference substance solution: Take an appropriate amount of glycyrrhizic acid monoammonium salt reference substance, accurately weigh it, add methanol to make a solution containing 0.1mg per 1ml, and obtain (0.09795mg converted into glycyrrhizic acid).

[0053] Preparation of the test solution: Accurately measure 10ml of this product, put it in a 25ml measuring bottle, add an appropriate amount of methanol, shake well, dilute to the mark with methanol, shake well, centrifuge, take the supernatant, and get ready.

[0054] Determination method: Precisely draw 10 μl each of the reference substance solution and the test solution, inject it into the liquid chromatograph, measure it, and obtain it. Each 1ml of this product contains licorice and glycyrrhizic acid (C 42 h 62 o 16 ) shall not be less than 0.12mg.

[0055] Functions and Indications: Moisturizing the lungs and clearing away heat, relieving cough and reducing phlegm. It is used for fever due to i...

Embodiment 2

[0058] Example 2 Instructions for Drafting Quality Standards for Pediatric Cough Syrup:

[0059] Pediatric Cough Syrup is an exclusive variety produced by Lerentang Pharmaceutical Factory of Tianjin Zhongxin Pharmaceutical Group Co., Ltd., and its current quality standards are recorded in Volume 15 of the Ministry of Health's Drug Standards for Traditional Chinese Medicine Prescriptions. In order to improve the quality standard of children's cough syrup compared with the ministerial standard, the TLC identification method of Scrophulariae Radix, Ophiopogon japonicus and Zhimu in the prescription was added, and the content determination method of licorice was formulated with ammonium glycyrrhizinate as the quantitative index. The drafting work will now be explained as follows:

[0060] 1 Prescription and Preparation: Revised. Revision content: According to 1000 preparation units, the prescription dosage is revised in proportion. According to the relevant provisions of the 200...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
The inside diameter ofaaaaaaaaaa
The inside diameter ofaaaaaaaaaa
Login to View More

Abstract

The invention belongs to the technical field of Chinese patent drug, relating to a quality control method for infantile cough syrup as Chinese medicine preparation, which is prepared from Chinese herbal medicines as raw materials, comprising the following steps: with the reference substances of figwort, lilyturf root and Sarsasapogenin, distinguishing whether the prescription of the infantile cough syrup contains the compounds of figwort, lilyturf root and Sarsasapogenin with thin layer chromatography; and with the reference substance of mono-ammonium glycyrrhizinate, detecting the content of glycyrrhizic acid in the prescription of the infantile cough syrup with high performance liquid chromatography; therefore, the quality standard is relatively perfect, and the quality control of the medicine is improved due to the amended quality standard.

Description

technical field [0001] The invention belongs to the technical field of Chinese patent medicines, and relates to a quality control method of a traditional Chinese medicine preparation children's cough syrup made from Chinese medicinal materials. Background technique [0002] Pediatric Cough Syrup is a classic Chinese patent medicine, listed in Volume 15 of the Ministry of Health’s Drug Standards for Traditional Chinese Medicine Prescriptions, Ministry of Health’s Standard WS 3 -B-2832-98 records the prescription and quality standards: [0003] Prescription: Scrophulariaceae 200g, Ophiopogon japonicus 200g, Dannanxing 200g [0004] Almond water 180ml Betel nut (charred) 150g Bellflower 150g [0005] Bamboo Ru 150g Mulberry Bark 150g Trichosanthin 150g [0006] Chuan Fritillaria 150g Melon Wilter 150g Licorice 150g [0007] Perilla seed (stir-fried) 100g Anemarrhena 100g Perilla leaf oil 0.32ml [0008] Preparation method: boil the above fifteen fla...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/899A61P11/14G01N30/90G01N30/36G01N30/02
Inventor 陈坚王磊赵艳李林
Owner 津药达仁堂集团股份有限公司乐仁堂制药厂
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com