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Automatic analyzing system

An automatic analysis device and cleaning solution technology, which is applied to the analysis of materials, instruments, etc., can solve the problem that the supply of cleaning solution cannot reach the predetermined amount

Active Publication Date: 2011-07-13
HITACHI HIGH-TECH CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Even if there is cleaning liquid, if the timing of supplying cleaning liquid to the nozzle (opening and closing timing of the piping valve for supplying cleaning liquid) deviates, there is a possibility that the supply of cleaning liquid will not reach the predetermined amount.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] figure 1 It is an example of a configuration diagram of an automatic analyzer to which the present invention is applied.

[0021] The sample probe 1 is connected to a dispensing syringe 3 through a tube 2, and their interiors are filled with a liquid. The dispensing syringe 3 includes a cylinder 3a and a plunger 3b, and the dispensing syringe driving mechanism 4 is connected to the plunger 3b. The cylinder 3a is fixed, and the plunger 3b is driven up and down by the dispensing syringe driving mechanism 4, whereby the sample dispensing operation is performed. In addition, the sample probe driving mechanism 5 is connected to the sample probe 1, whereby the sample probe 1 can be moved to a predetermined position. In addition, the dispensing syringe drive mechanism 4 and the sample probe drive mechanism 5 are controlled by the control unit 6 .

[0022] Now, the sample probe driving mechanism 5 and the sample probe 1 are lowered, and when they reach the liquid of the samp...

Embodiment 2

[0042] In recent years, automatic analyzers tend to dispensing micro-volumes, and the accuracy and reproducibility of the dispensing volumes ejected from the sample probe and the reagent probe are required.

[0043] However, the dispensing accuracy is not stable due to processing tolerances such as the inner diameter of the probe or the plunger of the syringe. Furthermore, the device tends to be miniaturized, and a relatively flexible tube such as silicon is provided inside the device. Of course, the same tube is used for connecting the sample probe from the sample syringe, and the thermal expansion of the tube makes the dispensing accuracy more unstable. That is, even dispensing accuracy errors due to conditions such as mechanical processing errors and environmental conditions that cannot be eliminated are required. In order to improve these, the operation correction can be performed based on the absolute value of the positive pressure in the washing water discharge obtained...

Embodiment 3

[0045] The life cycle of a general solenoid valve is about 3 million times, but it is expected to be used more times than that in an automatic biochemical analyzer. Furthermore, depending on the individual difference of the solenoid valve or the used liquid / environment, etc., the number of lifetimes may be shorter.

[0046] Figure 5 This is a diagram showing the phenomenon that occurs when the number of times the solenoid valve is used increases. The operation voltage here refers to the voltage at which the iron core (hereinafter referred to as plunger) in the solenoid starts to operate after the opening and closing command signal of the solenoid valve is turned ON. When the rated operating voltage is taken as 100%, the operating voltage of an unused solenoid valve is about 85%, and that of a solenoid valve with a lifetime of 3 million times is about 95%.

[0047] This operating voltage is causally related to the response time of the solenoid valve, which increases as the v...

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PUM

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Abstract

Disclosed is an automatic analyzing system, which is given a function to check whether the actions of individual portions thereof are being correctly executed or not. A pressure sensor is applied to a sample passage so that the action steps of a dispensing mechanism including the opening / closing of an electromagnetic valve can be checked in terms of a pressure waveform during a rinsing water discharge (10). Here, this function can also apply the pressure sensor which is used in a sample suction check of the prior art, as an additional function. Even with the ON / OFF failure of the electromagnetic valve, the discrimination can be made with an alarm so that the sample can be prevented from becoming thin, to thereby improve the data reliability.

Description

technical field [0001] The present invention relates to an automatic analyzer for qualitative and quantitative analysis of specific components in biological samples such as blood and urine, and more particularly to an automatic analyzer having a dispensing unit for dispensing a predetermined amount of liquid. Background technique [0002] Clinical examinations that analyze components contained in biological samples such as blood and urine of patients react the samples with reagents to perform qualitative and quantitative analysis of target components in the samples. In this case, a liquid supply mechanism called a dispensing mechanism is used to supply a predetermined amount of the sample and the reagent to the reaction container for reacting the sample and the reagent. As the liquid supply mechanism, use a pressure changing unit such as a syringe or a diaphragm to make the pressure in the nozzle that sucks the liquid a negative pressure, and after the suctioned liquid is su...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N35/10
CPCG01N2035/1018G01N35/1016G01N35/1004
Inventor 东信二西田正治福垣达也佐佐木博文铃木笃史
Owner HITACHI HIGH-TECH CORP
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