Unlock instant, AI-driven research and patent intelligence for your innovation.

Pharmaceutical composition for regulating liver and supplementing kidney, eliminating blood stasis and removing spot and preparation method of pharmaceutical composition

A composition and medicine technology, applied in the field of pharmaceutical compositions and their preparation, can solve the problems such as not being able to obtain satisfactory effects

Active Publication Date: 2013-03-27
SHANDONG DANHONG PHARMA
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the topical smears are health care products and skin care products, let alone obtain satisfactory results

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Pharmaceutical composition for regulating liver and supplementing kidney, eliminating blood stasis and removing spot and preparation method of pharmaceutical composition
  • Pharmaceutical composition for regulating liver and supplementing kidney, eliminating blood stasis and removing spot and preparation method of pharmaceutical composition
  • Pharmaceutical composition for regulating liver and supplementing kidney, eliminating blood stasis and removing spot and preparation method of pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0385] Embodiment 1: pharmaceutical composition capsule of the present invention

[0386] Bupleurum 333.3g Salvia 500g Rehmannia 500g

[0387] Angelica dahurica 333.3g, Moutan bark 333.3g, licorice 100g.

[0388] Get raw material medicine, cortex Moutan is distilled with 5000ml of water, collect the distillate of 3333ml, refrigerate at 0~10 ℃ for 8 hours, filter, get paeonol crystallization I, filtrate adds the sodium chloride of 5% of Cortex Moutan weight, Redistill, collect 1000ml of distillate, refrigerate at 0-10°C for 8 hours, filter to obtain paeonol crystals II, combine paeonol crystals I and II, and dry at 40°C to obtain paeonol. For standby, the filtrate A is collected in another device, and the dregs and the other five flavors of Bupleurum, Salvia, Rehmannia, Angelica, and Licorice are decocted twice, adding 10 times the weight of water for the first time, and 8 times the weight of water for the second time, each time Decoct for 2 hours, filter, combine the filtrat...

Embodiment 2

[0389] Embodiment 2: pharmaceutical composition tablet of the present invention

[0390] Bupleurum 310g Salvia 750g Rehmannia 350g

[0391] Angelica dahurica 390g, Moutan bark 310g, licorice 130g.

[0392] Get raw material medicine, cortex Moutan is distilled with 4650ml of water, collect the distillate of 3100ml, refrigerate at 0~10 ℃ for 8 hours, filter, get paeonol crystallization I, filtrate adds the sodium chloride of cortex moutan weight 5%, Redistill, collect 930ml of distillate, refrigerate at 0-10°C for 8 hours, filter to obtain paeonol crystals II, combine paeonol crystals I and II, and dry at 40°C at low temperature to obtain paeonol. For standby, the filtrate A is collected in another device, and the dregs and the other five flavors of Bupleurum, Salvia, Rehmannia, Angelica, and Licorice are decocted twice, adding 10 times the weight of water for the first time, and 8 times the weight of water for the second time, each time Decoct for 2 hours, filter, combine the...

Embodiment 3

[0393] Embodiment 3: pharmaceutical composition granule of the present invention

[0394] Bupleurum 390g Salvia 350g Rehmannia 750g

[0395] Angelica dahurica 310g, Moutan bark 390g, licorice 70g.

[0396] Get raw material medicine, cortex Moutan is distilled with 5850ml of water, collect the distillate of 3900ml, refrigerate at 0~10 ℃ for 8 hours, filter, get paeonol crystallization I, filtrate adds the sodium chloride of 5% of Cortex Moutan weight, Redistill, collect 1170ml of distillate, refrigerate at 0-10°C for 8 hours, filter to obtain paeonol crystals II, combine paeonol crystals I and II, and dry at 40°C to obtain paeonol. For standby, the filtrate A is collected in another device, and the dregs and the other five flavors of Bupleurum, Salvia, Rehmannia, Angelica, and Licorice are decocted twice, adding 10 times the weight of water for the first time, and 8 times the weight of water for the second time, each time Decoct for 2 hours, filter, combine the filtrates to o...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a pharmaceutical composition for regulating liver and supplementing kidney, eliminating blood stasis and removing spot, a preparation method, a quality testing method and use of the pharmaceutical composition. The pharmaceutical composition comprises the following raw material medicines of: radix bupleuri, red sage root, radix rehmanniae preparata, angelica dahurica, paenoia suffruticosa and glycyrrhiza. The preparation method comprises the following steps of: distilling the paeonia suffruticosa to get crystal, decocting the other raw material medicines with water, concentrating to obtain concrete, mixing the concrete with the crystal to prepare into various preparation formulations which are acceptable clinically. The quality testing method of the pharmaceutical composition comprises identifying one or more of methods for determining contents of propanoic acid and paeonol. A pharmacological experiment shows that the pharmaceutical composition of the invention has the function of nourishing skin and removing spot, and can effectively restrain the proliferation of B16 cells, the activity of tyosinase of B-16 melanoma cell strain, the formation of melanin, and the formation of the skin injury model mouse serum lipid peroxide caused by ultraviolet irradiation so as to cure the chloasma.

Description

field of invention [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a pharmaceutical composition capable of regulating the liver and tonifying the kidney, removing blood stasis and removing freckles, a preparation method, a quality detection method and an application thereof. Background technique [0002] Chloasma occurs in women from adolescence to menopause, especially due to work pressure and stressful life, which are more likely to cause the disease. This disease has affected the mental and physical health of vast numbers of women, so the treatment of this disease has attracted more and more attention. [0003] The etiology and pathogenesis of chloasma are still unclear. There are many factors involved in its pathogenesis, and the pathogenesis process is relatively complicated. Most of the clinical manifestations are facial hyperpigmentation caused by excessive expression of melanin and metabolic disorders. ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/804A61P17/00G01N30/90G01N30/36
Inventor 陈永泰
Owner SHANDONG DANHONG PHARMA