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Heat-clearing, anti-inflammatory and analgesic herb extract

An anti-inflammatory, analgesic and extractive technology is applied in the field of Rauwolfia root extract and its preparation, and can solve many diseases such as fever, sore throat, headache, dizziness, sha, abdominal pain, vomiting and diarrhea, pruritus scabies, etc. problem, to achieve the effect of maintaining pharmacological activity and avoiding damage

Inactive Publication Date: 2011-09-28
HAINAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the past, most of the studies on Rauwolfia were only on the antihypertensive and sedative effects of Rauwolfia alkaloids
Rauwolfia is used in the folks in our country to treat many diseases such as cold, fever, sore throat, headache, dizziness, Sha syndrome, abdominal pain, vomiting and diarrhea, wind itching, sores and scabies, but no one has conducted research on the heat-clearing, anti-inflammatory and analgesic effects of Rauwolfia. Experimental research

Method used

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  • Heat-clearing, anti-inflammatory and analgesic herb extract
  • Heat-clearing, anti-inflammatory and analgesic herb extract
  • Heat-clearing, anti-inflammatory and analgesic herb extract

Examples

Experimental program
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Effect test

Embodiment 1

[0095] A kind of Rauwolfia root extract, it is made by following preparation steps:

[0096] After the roots of Rauvolwolfia hainanensis are naturally dried at room temperature and protected from strong light, they are crushed and sieved, and 50g of dry powder is taken, placed in an extraction container, and distilled water is added to 8 times the amount of medicinal materials, decocted for 1 hour, and the operation is repeated 3 times; the crude extract is obtained with gauze After filtration, the crude extract filtrate is concentrated under reduced pressure with a rotary evaporator, and the parameters of the rotary evaporator are set to: temperature 50°C, vacuum 70kPa; then slowly add 95% ethanol to the concentrated solution, and stir quickly until the concentration of ethanol in the concentrated solution The concentration is 70%, and when the concentrated solution is slowly lowered to room temperature, move it to the refrigerator and refrigerate overnight; filter the next da...

Embodiment 2

[0099] A kind of Rauwolfia root extract, it is made by following preparation steps:

[0100] Induce emetic Rauwolfia root, dry it naturally at room temperature, avoid strong light, crush it, take 100kg of dry powder, put it in an extraction container, add 5 times the amount of distilled water of the medicinal material, decoct for 0.8 hours, repeat the operation 3 times; the crude extract is filtered with gauze , the crude extract filtrate is concentrated under reduced pressure by a rotary evaporator, and the parameters of the rotary evaporator are set to: temperature 80°C, vacuum 50kPa; then slowly add 95% ethanol to the concentrated solution, and stir quickly until the concentrated solution ethanol concentration is 70 %, when the concentrated solution is slowly lowered to room temperature, move it to a 10°C freezer and refrigerate overnight; filter the next day, remove the filter residue, freeze the filtrate to -45°C, and then freeze-dry it by gradually increasing the temperat...

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Abstract

The invention relates to a heat-clearing, anti-inflammatory and analgesic herb extract, and specifically relates to a rauvolfia extract and its preparation method. And the preparation of the extract comprises the steps of: selecting rauvolfia, drying in the shade naturally and pulverizing; taking a proper amount of dried rauvolfia powder , adding 8-10 times amount of distilled water, and decocting in an appropriate container; filtering and condensing the filtrate; adding 95% ethanol, adjusting the ethanol concentration of the concentrated liquor to 70%, and allowing the liquor to stand overnight at a low temperature; filtering and removing the filter residue; freeze-drying the filtrate, thus obtaining freeze-dried powders as the product. The rauvolfia extract of the invention has an obvious effect in clearing heat, resisting inflammation and easing pain, and it can also be prepared into a heat-clearing, anti-inflammatory and analgesic medicine.

Description

technical field [0001] The invention relates to a heat-clearing, anti-inflammatory and analgesic traditional Chinese medicine extract, in particular to an extract of Rauwolfia root and a preparation method thereof. Background technique [0002] Rauvolfia is a general term for plants of the genus Rauvolfia in the family Apocynaceae. "Flora of China" records that there are 135 species of Rauwolfia in the world, most of which are distributed in the tropics and subtropics, and a few species are distributed in the temperate zone. There are 9 species, 4 varieties and 3 cultivated species in China. Fresh leaves treat colds and high fever, insomnia, dizziness and other diseases, bruises, sprains, and snake bites. They have the functions of clearing wind and heat, reducing liver fire, reducing swelling and detoxification, and are important southern medicines in my country. [0003] Since the 1930s, scholars at home and abroad have conducted a lot of research on this genus and discove...

Claims

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Application Information

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IPC IPC(8): A61K36/24A61P29/00A61K125/00
Inventor 刘平怀刘洋洋时杰杨勋郝宗娣陈德力汪春牛许琼情
Owner HAINAN UNIVERSITY
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