A kind of synchronous extraction method of total triterpenes and polysaccharides of Antrodia antrodia

A technology of simultaneous extraction and total polysaccharide, applied in pharmaceutical formulations, medical preparations containing active ingredients, plant/algae/fungus/moss components, etc., can solve the problems of high cost, short extraction time, high extraction temperature, and achieve dissolution Changes in performance, shortened extraction time, complete reaction and the effect of
CN108014143BActive Publication Date: 2021-04-06ZHEJIANG UNIV OF TECH

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
ZHEJIANG UNIV OF TECH
Publication Date
2021-04-06

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Abstract

The invention discloses a method for synchronously extracting total triterpenes and polysaccharides of Antrodia camphorata. The method comprises the following steps: taking fruit body powder of Antrodia camphorata, adding an alkaline grinding aid for ball milling to obtain the ball-milled powder; adding the ball-milled powder to In distilled water, at a constant temperature of 30-70°C, carry out a high-speed shear reaction at 5000-10000rmp for 5-20min, and centrifuge to obtain a supernatant; adjust the pH of the supernatant to acidity, stir evenly, and place it in a 4°C refrigerator to stand until After the precipitation is complete, filter to obtain filtrate and precipitate. The filtrate is concentrated and dried to obtain total polysaccharide extract, and the precipitate is naturally dried to obtain total triterpenoid extract. The extraction rate of the total triterpenes of Antrodia camphorata is as high as 13.72%, the extraction rate is increased by nearly 2 times, the extraction rate of polysaccharides is as high as 12.94%, and the extraction rate is increased by nearly 1 times.
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Description

[0001] (1) Technical field

[0002] The invention relates to an extraction method of effective components of fungi, in particular to a combined extraction method of total triterpenoids and polysaccharides of Antrodia camphorata.

[0003] (2) Background technology

[0004] Antrodia Cinnamomea is a unique wood-rot fungus in Taiwan. Studies have found that Antrodia Cinnamomea contains a variety of physiologically active components, the most important two being triterpenes and polysaccharides. There are more than 200 kinds of total triterpenes of Antrodia camphorata, which have anti-cancer, anti-inflammatory, anti-virus and liver protection effects. Antrodia camphorata polysaccharides have anti-cancer, immunity-enhancing, and anti-oxidation effects.

[0005] Total triterpenoids of Antrodia camphorata are easily soluble in organic solvents, and polysaccharides are easily soluble in water. At present, most of the traditional methods for preparing triterpenes and polysaccharides use ...

Claims

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