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Deficiency and dryness improving ultra-micro powder as well as production method and application thereof to preparation of medicament for preventing and treating climacteric hypertension

A high blood pressure and ultra-micro technology, applied in the field of medicine, can solve the problems of poor effect, unacceptable for patients, large fluctuation of blood pressure, etc., to achieve the effect of improving hot sweating, improving sleep state, and being easy to carry.

Inactive Publication Date: 2011-11-02
XINJIANG MEDICAL UNIV AFFILIATED HOSPITAL OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine mostly uses conventional antihypertensive drugs and supplementary estrogen for treatment, but the effect is not ideal. On the one hand, menopausal hypertension fluctuates greatly, and conventional antihypertensive drugs are difficult to control; on the other hand, there are many adverse reactions of estrogen, which are difficult for patients to accept
Western medicine has its disadvantages in the treatment of menopausal hypertension. It often can quickly reduce blood pressure and even return to normal. However, it is not effective in improving dizziness, headache and other symptoms, and blood pressure fluctuates greatly.
After simply using western medicine to lower blood pressure, the blood pressure drops to normal or close to normal level, but the clinical manifestations and symptoms do not improve significantly

Method used

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  • Deficiency and dryness improving ultra-micro powder as well as production method and application thereof to preparation of medicament for preventing and treating climacteric hypertension
  • Deficiency and dryness improving ultra-micro powder as well as production method and application thereof to preparation of medicament for preventing and treating climacteric hypertension
  • Deficiency and dryness improving ultra-micro powder as well as production method and application thereof to preparation of medicament for preventing and treating climacteric hypertension

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1, the Xuzao Gengping ultrafine powder used for preventing and treating menopausal hypertension is produced according to the following raw materials by weight: 224 to 248 parts by weight of mulberry, 180 to 198 parts by weight of rhodiola, 180 to 198 parts by weight of Xintahua, 180 to 198 parts by weight of Zhimu, 180 to 198 parts by weight of Prunella vulgaris, and 180 to 198 parts by weight of Achyranthes bidentata.

Embodiment 2

[0022] Example 2, the Xuzao Gengping ultrafine powder used for preventing and treating menopausal hypertension is produced according to the weight of the following raw materials: 224 parts by weight of mulberry, 180 parts by weight of Rhodiola rosea, 180 parts by weight of Xintahua, 180 parts by weight of female, 180 parts by weight of Prunella vulgaris, 180 parts by weight of Achyranthes bidentata.

Embodiment 3

[0023] Example 3, the Xuzao Gengping ultrafine powder used for preventing and treating menopausal hypertension is produced in parts by weight of the following raw materials: 248 parts by weight of mulberry, 198 parts by weight of Rhodiola rosea, 198 parts by weight of Xintahua, 198 parts by weight of Anemarrhena anemarrhena 198 parts by weight, 198 parts by weight of Prunella vulgaris, and 198 parts by weight of Achyranthes bidentata.

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Abstract

The invention discloses deficiency and dryness improving ultra-micro powder as well as a production method and application thereof to preparation of a medicament for preventing and treating climacteric hypertension. The deficiency and dryness improving ultra-micro powder is prepared by the following steps of: drying demand quantities of mulberry, rhodiola rosea, anemarrhena rhizome, selfheal spike and radix achyranthis bidentatae at low temperature and crushing to obtain medicinal material fine powder by using an ultra-micro crusher; cutting up a demand quantity of ziziphora bungeana, then extracting volatile oil by using a steam distillation method, and performing inclusion on the obtained volatile oil and beta-cyclodextrin to obtain a volatile oil inclusion compound by using a grinding method; and fully mixing the medicinal material fine powder obtained by the steps and the volatile oil inclusion compound to obtain the deficiency and dryness improving ultra-micro powder. The deficiency and dryness improving ultra-micro powder has the characteristics of effectively preventing and treating and improving the symptoms of a female climacteric hypertension patient and effectively improving a series of clinical symptoms such as reheat sweating, irritability, dizziness, dryness of mouth and thirstiness, insomnia and palpitation and the like, and is convenient to carry and easy to produce.

Description

Technical field [0001] The invention is a pharmaceutical technology field. It is a kind of deficiency and dry micro -loose agent and its production methods and the application of menopausal hypertension drugs. Background technique [0002] Hypertension is the most common cardiovascular disease. It is a major public health problem globally. It is one of the common cardiovascular disease that endangers human health.Symptoms have a huge burden on society and families.China is the country with the worst harm to high blood pressure. According to the latest China Nutrition and Health Survey, it is estimated that the number of patients exceed 200 million.Faced with the incidence and severe complications of such high blood pressure, the control rate of China's hypertension is extremely low, and only 6.1 % of patients who can control blood pressure to normal range. [0003] Menopausal hypertension is a hypertension that belongs to special groups. There are many clinical symptoms, which se...

Claims

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Application Information

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IPC IPC(8): A61K36/8964A61P9/12
Inventor 林雪何佳张海英许红峰马丽
Owner XINJIANG MEDICAL UNIV AFFILIATED HOSPITAL OF CHINESE MEDICINE
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