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Biological degradable self-expansive fallopian tube intrauterine device produced by natural synthesis composite materials

A technology for composite materials and IUDs, which is applied in the field of preparing biodegradable self-expandable fallopian tube IUDs from natural and synthetic composite materials, achieving the effects of short preparation process, high economic benefits and simple operation

Active Publication Date: 2013-01-02
LUOHE SHUGUANG HUIZHIKANG BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no report on the preparation of a degradable self-expandable fallopian tube IUD by natural and synthetic polymer composite materials at home and abroad

Method used

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  • Biological degradable self-expansive fallopian tube intrauterine device produced by natural synthesis composite materials
  • Biological degradable self-expansive fallopian tube intrauterine device produced by natural synthesis composite materials

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A method for preparing a biodegradable self-expandable fallopian tube IUD from natural and synthetic composite materials, comprising the steps of:

[0036] (1) 100,000 polylactic acid with a molecular weight of 99Kg and 1Kg of aluminum-free baking powder are dissolved in chloroform, and a uniform solution is obtained under stirring. The mass ratio of polylactic acid with a molecular weight of 100,000 and chloroform is 5:95;

[0037] (2) Place the solution obtained in step (1) in an oven, and foam at 75°C for 60 minutes to obtain a degradable self-expanding sponge-like structure;

[0038] (3) Cut the spongy structure into a cylinder with a diameter of 1.0 mm and a length of 40 mm, then soak it in an aqueous chitosan solution with a mass concentration of 3%, soak for 30 minutes, and take it out to obtain a natural and synthetic compound Materials to prepare biodegradable self-expandable fallopian tube IUD.

[0039] The IUD is compressible with a diameter compression rat...

Embodiment 2

[0041] A method for preparing a biodegradable self-expandable fallopian tube IUD from natural and synthetic composite materials, comprising the steps of:

[0042] (1) Polylactic acid with 130,000 molecular weight of 99Kg and 1Kg food-grade sweet baking powder are dissolved in chloroform, obtain uniform solution under stirring, the mass ratio of polylactic acid with molecular weight 130,000 and chloroform is 10: 90;

[0043] (2) Place the solution obtained in step (1) in an oven, and foam at 25°C for 120 minutes to obtain a degradable self-expanding sponge-like structure;

[0044] (3) Cut the spongy structure into a cylinder with a diameter of 0.3 mm and a length of 10 mm, then soak it in an aqueous chitosan solution with a mass concentration of 5%, soak for 30 minutes, and take it out to obtain a natural and synthetic compound Materials to prepare biodegradable self-expandable fallopian tube IUD.

[0045] The IUD is compressible, and the compression ratio of the diameter is ...

Embodiment 3

[0047] A method for preparing a biodegradable self-expandable fallopian tube IUD from natural and synthetic composite materials, comprising the steps of:

[0048] (1) Polylactic acid with a molecular weight of 150,000 of 98Kg and 2Kg food grade aluminum-free baking powder are dissolved in chloroform, and a uniform solution is obtained under stirring. The mass ratio of polylactic acid with a molecular weight of 150,000 and chloroform is 15 : 85;

[0049] (2) Place the solution obtained in step (1) in an oven and foam at 120°C for 5 minutes to obtain a degradable self-expanding sponge-like structure;

[0050] (3) Cut the spongy structure into a cylinder with a diameter of 0.5 mm and a length of 30 mm, then soak it in an aqueous chitosan solution with a mass concentration of 7%, soak for 30 minutes, and take it out to obtain a natural and synthetic compound Materials to prepare biodegradable self-expandable fallopian tube IUD.

[0051] The IUD is compressible with a diameter co...

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Abstract

The invention discloses a biological degradable self-expansive fallopian tube intrauterine device produced by natural synthesis composite material, which takes degradable materials and foaming agent with the mass ratio of 98-99.99 / 0.01-2 as raw materials to produce a degradable self-expansive spongeous structure, the spongeous structure is cut into a cylinder, and the surface of the cylinder is coated with a chitosan layer. The intrauterine device is degradable, the fallopian tube gets unobstructed, so fertilization is realized again, and the intrauterine device is more suitable for women whoreach child bearing age, plan short-term contraception and do not will to adopt other contraception measures; the intrauterine device is softer, and cannot damage the tissue of the fallopian tube; suitable expansion force is kept, so the intrauterine device is convenient to be firmly attached to the inner wall of the fallopian tube and cannot generate larger expansion force on the wall of the fallopian tube; and the intrauterine device has shorter production method and flow, is simple to operate, has low cost and is environmentally friendly.

Description

technical field [0001] The invention belongs to the field of biodegradable medical materials, in particular to a biodegradable self-expandable fallopian tube IUD prepared from natural and synthetic composite materials. Background technique [0002] Tubal sterilization is one of the commonly used methods for human birth control, and it has played an important role in controlling population growth because of its advantages of safety, reliability and permanence. It is estimated that more than 100 million women of childbearing age around the world use this method for sterilization. In the United States, Central America and East Asian countries, tubal sterilization has accounted for 30-33% of contraceptive measures. With the increase of social divorce rate and remarriage rate and the increase of social factors that may cause premature child deaths, the majority of women are less and less accepting of tubal sterilization. They hope to have a convenient, safe, effective contracepti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F6/22A61L31/06A61L31/10
Inventor 付正英杨庆
Owner LUOHE SHUGUANG HUIZHIKANG BIOTECH