Traditional Chinese medicine oral solution for prevention and treatment of avian colibacillosis and preparation method of same

Abstract

The invention discloses a traditional Chinese medicine oral solution for the prevention and treatment of avian colibacillosis and a preparation method of the same. The preparation method comprises the following steps of: refluxing and extracting Chinese herbal medicines for two times, wherein, for the first time, water is added into the Chinese herbal medicines by weight 10 folds more than the later, the Chinese herbal medicines are refluxed and extracted for 1.5 hours, and are filtered; and for the second time, water is added into the Chinese herbal medicines by weight 8 folds more than the later, the Chinese herbal medicines are refluxed and extracted for 1 hour, and are filtered, filtrate is stewed overnight; combining filtrate refluxed and extracted at the two times; concentrating thefiltrate; adding ethanol to precipitate the filtrate; concentrating supernate; recovering the ethanol to have no alcohol flavor; adding a flavoring agent; adjusting the pH value to 5; adjusting the total volume by using water for injection, equivalent to 1g / mL raw herbs; uniformly mixing the solution; and filling and sterilizing the solution. In consideration of special physiological structures of a short genital tract and incapability of digesting wood fiber of poultry, the medicine is prepared into the oral solution, can be administered to sick poultry in a manner of drinking water, gavage,mixing with feed, is convenient, and is favorable for absorption; and the purpose of quickly taking effect can be achieved.

Description

technical field [0001] The invention relates to a traditional Chinese medicine oral liquid for preventing and treating poultry colibacillosis and a preparation method thereof, belonging to the technical field of poultry disease prevention and control. Background technique [0002] Avian colibacillosis is a common disease caused by Escherichia coli, characterized by pericarditis, perihepatitis, air sac inflammation, peritonitis, salpingitis, synovitis, E. coli granuloma and omphalitis, etc. lesion. Escherichia coli is a common bacterium in the intestinal tract of healthy livestock and poultry, which can be divided into two categories: pathogenic and non-pathogenic. Escherichia coli disease is a conditional disease, which is easily caused by poor sanitation and poor feeding and management. Escherichia coli has strong resistance to the environment, and Escherichia coli attached to feces, soil, dust in pens, fluff of incubators, broken egg skins, etc. can survive for a long ti...

AI Technical Summary

Problems solved by technology

Veterinary drug manufacturers produce according to the Pharmacopoeia and cannot flexibly change the actual situation in poultry production

At the same time, there are many types of traditional Chinese medicines in prescribed prescriptions, and the prices are high, which limits the use of traditional Chinese medicines.

[0008] Traditional Chinese medicines for poultry are mostly powders, but because the specific surface of the medicine is larger after being crushed, its smell, taste, irritation, hygroscopicity and chemical activity also increase accordingly, making some medicines easy to change; volatile components easily lost

When farmers use it, if they use powder to mix, it is used for short intestines of poultry, and the absorption of traditional Chinese medicine is not complete; if it is decocted and filtered, it is inconvenient to prepare and delays the treatment time

[0009] Escherichia coli is very easy to develop resistance to antibacterial drugs. In the late stage of E. coli disease, if there are more serious pathological changes such as air sacculitis, perihepatitis, and yolk peritonitis, the efficacy of antibiotics is often not significant or even ineffective.

At the same time, excessive use of antibacterial drugs will remain in poultry and egg products, which will affect human health