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Paracetamol-caffeine-artificial cow-bezoar-chlorphenamine maleate medicinal composition and preparation method thereof

A composition and drug technology, applied in the new field of drugs, can solve the problems of slow onset of action and poor bioavailability, and achieve the effect of good drug effect and rapid disintegration and dissolution

Inactive Publication Date: 2012-03-14
JILIN AODONG GROUP DALIAN PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, its common dosage form has poor bioavailability and slow onset of action.

Method used

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Examples

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Effect test

Embodiment Construction

[0013] The following examples illustrate the present invention's acetaminophen-sensitized pharmaceutical composition and its preparation method.

[0014] The medicinal composition of aminoca yellow allergy contains acetaminophen, artificial bezoar, chlorpheniramine maleate, and caffeine in a weight ratio of 100:4:0.4:6; adding auxiliary fillers, disintegrants, and flavoring agents 20%.

[0015] A method for preparing the above-mentioned aminocarbaflagellate pharmaceutical composition, comprising the following steps:

[0016] Weigh acetaminophen, artificial bezoar, chlorpheniramine maleate, and caffeine, mix them uniformly in a weight ratio of 100:4:0.4:6, add 20% auxiliary materials, granulate, dry, and granulate.

[0017] The above is only a preferred embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Anyone familiar with the technical field within the technical scope disclosed in the present invention, according...

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PUM

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Abstract

The invention discloses a paracetamol-caffeine-artificial cow-bezoar-chlorphenamine maleate medicinal composition and a preparation method thereof. The paracetamol-caffeine-artificial cow-bezoar-chlorphenamine maleate medicinal composition medicinal composition comprises paracetamol, caffeine, chlorphenamine maleate and artificial cow-bezoar in the weight ratio (90-160):(3-7):(0.1-0.6):(5-10); and a filling agent, a disintegrating agent and a flavoring agent serving as auxiliary materials can be added. The method for preparing the paracetamol-caffeine-artificial cow-bezoar-chlorphenamine maleate medicinal composition comprises the following steps of: weighing paracetamol, artificial cow-bezoar, chlorphenamine maleate and caffeine; mixing uniformly; adding 10-20 percent of auxiliary materials; and pelletizing, drying and straightening. The prepared paracetamol-caffeine-artificial cow-bezoar-chlorphenamine maleate medicinal composition has high disintegrating and dissolving speeds and a good medicament effect, and is used for treating nasal obstruction, headache, sore throat, fever and the like.

Description

technical field [0001] The invention belongs to the field of new medicine technology, and in particular relates to an aminocarbaflammine pharmaceutical composition and a preparation method thereof. Background technique [0002] Influenza is a common clinical disease and frequently-occurring disease, which is caused by exogenous evils invading the human body with headache, nasal congestion, runny nose, sneezing, aversion to wind and cold, heating, floating pulse, etc. as the main clinical manifestations. Cold is also a kind of acute infectious rhinitis, commonly known as "cold". It is caused by respiratory viruses, among which coronavirus and rhinovirus are the main pathogenic viruses. The virus is excreted and spread from respiratory secretions. When the body's resistance decreases, such as cold, malnutrition, excessive fatigue, excessive smoking and alcohol, systemic diseases, and chronic diseases of the nose itself that affect the smoothness of the respiratory tract, infe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/413A61K9/16A61K47/38A61K47/36A61K47/32A61P11/00A61P29/00A61K31/167A61K31/4402A61K31/522
Inventor 刘德胜
Owner JILIN AODONG GROUP DALIAN PHARMACEUTICAL CO LTD
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