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Compound medicine for treating rheumatism and preparation method thereof

A technology for rheumatism and medicine, applied in the field of compound medicine for treating rheumatism and its preparation, can solve problems such as difficulty in taking into account rheumatism, rheumatoid arthritis, unsuitable for long-term use by patients, high toxicity and side effects, etc.

Active Publication Date: 2012-04-25
新疆维吾尔药业有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, rheumatism and rheumatoid arthritis are chronic diseases, and the pathological changes in each stage of the development process are not the same. It is difficult for a single drug to take into account the whole process of rheumatism and rheumatoid arthritis. toxicity and side effects, not suitable for long-term use by patients

Method used

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  • Compound medicine for treating rheumatism and preparation method thereof
  • Compound medicine for treating rheumatism and preparation method thereof
  • Compound medicine for treating rheumatism and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Example 1 (Preparation of tablets based on the preparation of 1000g, enumerated in the form of a table)

[0014] The selected capers, ali red, box fruit vine, and Peganum harmala are mixed and crushed to 20 meshes, and extracted twice with 10 times the amount of water, at a temperature of 80°C, and each extraction time is 1 hour, and precipitation with ethanol , The concentration of alcohol precipitation is 50%, filter, recover the solvent, concentrate, and dry, that is, the dry extract is pulverized into powder, fully mixed with auxiliary materials, and made into tablets according to conventional methods.

[0015]

[0016] Note: PVP in the table is sodium carboxymethyl starch and povidone

Embodiment 2

[0017] Example 2 (based on the preparation of 1000g)

[0018] The selected capers, ali red, box fruit vine, and Peganum harmala are mixed and crushed to 50 meshes, and extracted twice with 8 times the amount of 50% ethanol solution at a temperature of 40°C, and each extraction time is 1 hour. The solvent is recovered, concentrated and dried, that is, the dry extract is pulverized into powder, thoroughly mixed with the auxiliary materials, and made into tablets according to the conventional method.

[0019]

[0020] Note that CMS-Na and PVP in the table are sodium carboxymethyl starch and povidone respectively.

Embodiment 3

[0021] Example 3 (based on the preparation of 1000g)

[0022] The preparation method is the same as in Example 1, and the capsules are made according to the conventional method.

[0023]

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PUM

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Abstract

The invention relates to a compound medicine for treating rheumatism and a preparation method thereof. The compound medicine is prepared by the following steps of: taking caper, fmoes officinalis ames, operculina turpethum and peganum harmala as raw material medicines, and starch, dextrin, povidone, sodium stearate, vegetable oil, glycerin gelatine, sodium carboxymethyl starch, liquid paraffin orshellac as auxiliary materials, carrying solvent extraction, decontaminating, concentrating, drying, preparing into tablets, capsules, pills or oral preparations. The rheumatism comprises rheumatoid arthritis, rheumatoid arthritis, sciatica as well as bone and joint pain. In the compound medicine disclosed by the invention, according to the theory of traditional Chinese medicine, with the characteristics of medicine of ethnic minorities, on the basis of the long-term folk clinical practical of the ethnic minorities, effective components in the compound medicine are dissolved out by a reasonable extracting method, so that the medicinal effect is strengthened, the biological utilization rate is improved, and convenience is provided for patients.

Description

Technical field [0001] The invention relates to a compound medicine for treating rheumatism and a preparation method thereof, and belongs to the technical field of ethnic medicine. Background technique [0002] Rheumatism, including rheumatoid arthritis, rheumatoid arthritis, sciatica, and bone and joint pain is a common long-term chronic disease. Its clinical manifestations include pain, swelling, and decreased function of the affected joints. The disease is persistent and recurrent. In severe cases, it can cause the human body to lose labor or even become disabled. The local disability rate is over 60%, which seriously endangers public health. At present, the purpose of treatment of such diseases is to relieve joint symptoms, delay the progression of the disease, reduce the occurrence of disability, maintain joint function as much as possible, and improve the quality of life of patients. Clinically, the main conventional drugs for this type of disease are: non-steroidal anti-i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P19/02A61P29/00
Inventor 阿吉艾克拜尔・艾萨祖里皮亚・塔来提李名学刘腊才蒋岚
Owner 新疆维吾尔药业有限责任公司
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