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3 results about "Peganum harmala" patented technology

Peganum harmala, commonly called wild rue, Syrian rue, African rue, esfand, or harmel, (among other similar pronunciations and spellings), is a perennial, herbaceous plant, with a woody underground root-stock, of the family Nitrariaceae, usually growing in saline soils in temperate desert and Mediterranean regions. Its common English-language name came about because of a resemblance to rue (which is not related). Because eating it can cause livestock to sicken or die, it is considered a noxious weed in a number of countries. It has become an invasive species in some regions of the western United States. The plant is popular in Middle Eastern and north African folk medicine. The alkaloids the plant, including the seeds, contains are hallucinogenic, possibly due to a monoamine oxidase inhibitor, thus it is sold in the West for recreational drug use.

Method for peeling peganum harmala seeds

The application provides a peeling method of blueberry kernels, which comprises the following steps: first, soaking dry blueberry kernels in acid with a preset concentration at a preset mass ratio, and continuously stirring; then, peeling the soaked blueberry kernels by using a peeling machine to obtain peeled blueberry kernels; finally, drying the obtained peeled blueberry kernels to obtain finished products. The application utilizes the interaction of lemon acid soaking, combined flushing of normal pressure and high pressure, and low-temperature baking, forms a gap between the blueberry kernels and the peel, realizes efficient peeling by using the combined flushing mode of normal pressure and high pressure, and finally, low-temperature drying, which not only avoids the heat damage of high temperature to the blueberry kernels, but also adapts to different specifications of blueberries, and the obtained blueberry products not only have a high peeling rate, but also have a good taste and a high nutritional value; meanwhile, the color of the obtained finished products is uniform, only a small amount of color is mixed, thereby improving the application of the blueberries in various mixed nutritional products or solid beverages.
Owner:JIANGNAN UNIV +1

Application of alkaloid compound in preparation of product with effect of resisting respiratory syncytial virus

The invention belongs to the technical field of medicinal chemistry, and particularly relates to application of an alkaloid compound in preparation of a product with a respiratory syncytial virus resisting effect. The alkaloid compound with a brand new chemical structure is extracted from peganum harmala, the compound shows very remarkable respiratory syncytial virus resistance activity, and the activity intensity of the compound is equivalent to that of a positive drug ribavirin. Meanwhile, the selection index (SI value) of the compound is greater than 13.8, which indicates that the safety range of the compound is larger, and the use safety can be better guaranteed while the drug effect is exerted. Therefore, the compound serving as an active ingredient is used for preparing medicines or health-care products with the effect of resisting the respiratory syncytial virus, and has important application value and wide development prospect.
Owner:THE FIRST AFFILIATED HOSPITAL OF JINAN UNIV CHAOSHAN HOSPITAL

Compositions targeting glp-1 receptor and use thereof in the treatment of metabolic diseases

PendingCN122342772ADiseaseReceptor
The present application relates to the technical field of biological medicine, and particularly relates to a composition taking GLP-1 receptor as a target point, which comprises the following raw materials in parts by weight: gentiana scabra extract 10-25 parts, andrographolide sulfonate 5-15 parts, peganum harmala alkaloid 3-7 parts, curcumin functional compound 20-40 parts, and excipients; the excipients comprise sodium caprate 4-8 parts and konjac glucomannan 8-15 parts. The composition of the present application realizes the ordered synergistic effect in time and space through the triple mechanism of "promoting endogenous GLP-1 secretion at the intestinal end, directly activating GLP-1R at the receptor end and prolonging the half-life, and promoting beta cell regeneration and protection at the effector organ end", reshapes the steady-state regulation ability of the body's own GLP-1 signal axis, improves sugar metabolism, and is suitable for the prevention and treatment of diabetes, obesity and related metabolic diseases.
Owner:BEIJING BEISIKANG PHARM TECH CO LTD