Peganum harmala L extract chewable tablets and preparation method thereof

A technology of extracts and chewable tablets, which is applied in the field of chewable tablets and its preparation, can solve the problems of failure to achieve the expected medicinal purpose, low utilization rate of medicinal active ingredients, inconvenience for patients to swallow, etc., and achieve high yield and effective Fast, low-cost production results

Inactive Publication Date: 2010-07-21
日照金禾生化集团股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, the existing medicinal products of Camelina all adopt the form of direct administration, in which the utilization rate of medicinal active ingredients is low, and the expected medicinal purpose cannot be achieved, and because of the taste of the medicine itself, it is very inconvenient for users to use , and it is not convenient for patients to swallow. In order to develop the medicinal resources of Camelia chinensis, a way to effectively utilize it is urgently needed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Take 500g of camel basil powder, add 7.5kg of water, soak for 10 hours, then reflux for 8 hours, after reflux is completed, cool, concentrate the extract to 1 / 40 of the original weight, add 100g of chloroform for extraction, until the extract is colorless, combine The extract is concentrated to obtain the extract of camel basil.

[0024] Take 100g of camel seed extract, 400g of mannitol, 5g of stevioside, 5g of orange essence, spray it with water, mix well, send it to the granulation mechanism, dry the granules at 30-80°C, add to the dry granules Micropowder silica gel 3g, mix and send into a tablet machine to form a chewable tablet of camel seed extract.

Embodiment 2

[0026] Take 500g of camel basil powder, add 7.5kg of water, soak for 10 hours, then reflux for 8 hours, after reflux is completed, cool, concentrate the extract to 1 / 40 of the original weight, add 100g of chloroform for extraction, until the extract is colorless, combine The extract is concentrated to obtain the extract of camel basil.

[0027] Take 100g camel seed extract extract, 400g sorbitol, 5g glycyrrhizin, 5g lemon essence, spray with water, mix evenly, send it to the granulation machine granules, dry the granules at 30-80°C, put them in the dry granules Add 3g of magnesium stearate, mix well and send into a tablet machine to form tablets of Camelina extract chewable tablets.

Embodiment 3

[0029] Take 500g of camel basil powder, add 7.5kg of water, soak for 10 hours, then reflux for 8 hours, after reflux is completed, cool, concentrate the extract to 1 / 40 of the original weight, add 100g of chloroform for extraction, until the extract is colorless, combine The extract is concentrated to obtain the extract of camel basil.

[0030] Take 100g of camel basil extract extract, 400g of lactose, 5g of saccharin, 5g of spearmint oil, spray it with water, mix evenly, send it to the granulation mechanism, dry the granules at 30-80°C, and add talc to the dry granules Powder 3g, mix and send into tablet machine and make the chewable tablet of camel seed extract.

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PUM

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Abstract

The invention relates to the technical field of medicine, providing a method for preparing peganum harmala L extract chewable tablets. The chewable tablets use peganum harmala L extract as active components, with the aid of other pharmaceutical excipients which include diluents, sweetening agents, taste-masked agents, lubricants, etc. The chewable tablets have the advantages of good taste, convenient usage, fast absorption, rapid effect and high bioavailability. The chewable tablets have multiple pharmacological effects, such as antisepsis, antiphlogosis, antipruritic effect, anti-protozoan, effects on central nervous systems, cardiovascular systems, muscle ion channels, etc. The chewable tablets have better application prospect.

Description

Technical field: [0001] The invention relates to a chewable tablet mainly made of camel seed extract and a preparation method thereof, belonging to the technical field of medicine. Background technique: [0002] Peganum harmala (peganum harmala L) is a perennial herbaceous plant belonging to the genus peganum of the family zygophyllaceae, and is mainly distributed in the northwest region of China. The whole herb can be used as medicine, and it is mainly used to treat cough and asthma, inexplicable swelling and pain, rheumatic joint pain and other diseases. The pharmacologically active components of Camelina are mainly alkaloids. In recent years, its anti-tumor effect has attracted the attention of scholars at home and abroad, and has become one of the research hotspots. [0003] The pharmacological effects of the camel alkaloids are relatively extensive, with antibacterial, anti-inflammatory, antipruritic, antiprotozoal, and various pharmacological effects on the central ne...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61K9/20A61P9/00A61P17/04A61P21/00A61P25/00A61P31/04A61P33/02
Inventor 秦大伟王利振
Owner 日照金禾生化集团股份有限公司
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