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Medicinal composition for preventing and treating skin eczema and skin pruritus, formulation and application

A skin eczema and composition technology, which is applied in the field of pharmaceutical compositions for preventing and treating skin eczema and skin pruritus, can solve the problems of high treatment cost, poor curative effect, and easy recurrence, and achieves simple preparation process, prevention and treatment of skin eczema, good and moisturizing effect

Active Publication Date: 2012-04-25
THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, antiallergic drugs such as chlorpheniramine are often used clinically to treat skin pruritus, but dry mouth and lethargy may occur after taking the medicine.
However, a large number of traditional Chinese medicine preparations used for the treatment of eczema and pruritus in the prior art have defects such as poor curative effect, easy recurrence, long course of treatment, and high treatment cost.

Method used

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  • Medicinal composition for preventing and treating skin eczema and skin pruritus, formulation and application
  • Medicinal composition for preventing and treating skin eczema and skin pruritus, formulation and application
  • Medicinal composition for preventing and treating skin eczema and skin pruritus, formulation and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Composition of prescription:

[0027]

[0028]

[0029] The preparation method is as follows: stearic acid and beeswax are mixed and heated to 90°C as the oil phase, cooled to about 70°C, added with the propolis extract and hemp oil, and stirred; emulsifier, glycerin, water, etc. are mixed and heated to 90°C as the water phase, and added Scutellaria baicalensis extract and glycyrrhizin, cool to about 70°C; the mixing method can be the oil phase added to the water phase, or the water phase can be added to the oil phase, mix, and cool to about 45°C; menthol and camphor are combined into a liquid , Add to the above mixture, stir well and get it.

Embodiment 2

[0031] Composition of prescription:

[0032]

[0033] The preparation method is that cocoa butter, light liquid paraffin, and white petrolatum are mixed and heated to 90°C as the oil phase, and cooled to about 70°C. Propolis extract, propylparaben and hemp oil are added; borax, sodium sulfite, methylparaben , Water, etc., mix and heat to 90°C as the water phase, add the scutellaria baicalensis extract and glycyrrhizin, and cool to about 70°C; add the water phase to the oil phase, stir evenly, cool to about 50°C, add the essence, and stir well. Pack it when it is cooled to 30~40℃.

Embodiment 3

[0035] Composition of prescription:

[0036]

[0037] The preparation method is stearic acid, white petrolatum, glyceryl monostearate, stearyl alcohol, Pingjia, silicone oil, and azone, mixed and heated to 90°C as the oil phase, cooled to about 70°C, added hemp oil and propolis extract, Stir well; glycerin, scutellaria baicalensis extract, glycyrrhizin, water, etc. are mixed and heated to 90°C as the water phase, and cooled to about 70°C; the water phase is added to the oil phase, or the oil phase can be added to the water phase and stirred. , Cool to about 50°C, add the co-grinding solution of menthol and camphor, add preservatives, antioxidants and flavors, stir well, and pack it when it is still cooled to 30-40°C.

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Abstract

The invention relates to the technical field of Chinese medicines, in particular to a medicinal composition for preventing and treating skin eczema and skin pruritus, a formulation and application. The medicinal composition comprises the following substances in part by weight: 5 to 30 parts of glycyrrhizin, 5 to 30 parts of baical skullcap root extract, 5 to 30 parts of propolis extract and 10 to 100 parts of hemp seed oil. The medicinal composition comprises a Chinese medicinal composition and a pharmaceutically acceptable carrier; and the formulation is an emulsion, cream, a tincture, distillate medicinal water, a liniment, a lotion, a film coating agent or a spray. The invention also relates to the application of the medicinal composition and the formulation to the preparation of a medicine for preventing and treating the skin eczema and the skin pruritus. The invention has the advantages that: the preparation process is simple, and the medicine has uniform and stable quality; and the medicinal composition can effectively prevent and treat the skin eczema and the skin pruritus, has the effect of inhibiting and / or killing various bacteria and viruses, and has good effects of maintaining skin moisture and moistening at the same time.

Description

Technical field [0001] The invention belongs to the technical field of pharmaceutical compositions for preventing and treating skin eczema and pruritus derived from traditional Chinese medicine, and specifically relates to a pharmaceutical composition, dosage form and application for preventing and treating skin eczema and pruritus. Background technique [0002] Eczema is a common inflammation of the superficial dermis and epidermis. It may be caused by external physical, chemical irritation or self-allergic constitution, which has obvious tendency to exudate allergic skin inflammation. Patients' skin is often characterized by pleomorphism, intense itching, recurring attacks, and chronicity. Clinically, it can be divided into three stages: acute, subacute and chronic according to its onset stage. According to the main skin lesions, there are erythematous eczema, hemorrhagic eczema, water sore eczema, erosive eczema, impetigo eczema, scaly eczema, etc. Depending on the location...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/60A61P17/00A61P17/04A61P37/08A61P29/00A61P31/04A61P31/12A61K31/704A61K31/045A61K31/125A61K35/64A61K35/644
Inventor 刘峰群周旭韩晋
Owner THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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