Multi-parameter-based intracranial pressure noninvasive detection method and device

Abstract

The invention provides a multi-parameter-based intracranial pressure noninvasive detection method and device. The method comprises the following steps of: pre-establishing an intracranial pressure evaluation function model for recording a function mapping relation between the change of the intracranial pressure and the changes of an electrocardiosignal, a visual evoked potential signal, a brain impedance signal and a transcranial Doppler ultrasonic signal and setting in a computer; and synchronously acquiring the electrocardiosignal, the visual evoked potential signal, the brain impedance signal and the transcranial Doppler ultrasonic signal into a computer and inputting the signals serving as the intracranial pressure evaluation function model to obtain the dynamic change process waveform of the intracranial pressure of an inspected object by performing multi-parameter and multi-direction operation. Due to the adoption of the method, invasive intracranial pressure detection is avoided; the device for implementing the method is easy to obtain; and meanwhile, various physiological and pathological signal parameters causing the change of the intracranial pressure are considered comprehensively in the intracranial pressure evaluation function model, so that the intracranial pressure noninvasive detection method has higher clinical detection accuracy.

Description

technical field [0001] The invention relates to the fields of biomedical engineering technology and information processing technology, in particular to a multi-parameter-based non-invasive detection method and device for intracranial pressure. Background technique [0002] Intracranial hypertension is a major cause of secondary brain injury, and its degree and duration have been shown to correlate with survival rates, degree of permanent dysfunction, and especially when the intracranial volume-pressure curve reaches a critical point, as long as the cranial A small change in the internal volume will lead to a sharp increase in intracranial pressure, aggravating brain displacement and brain herniation, and a crisis of central nervous system failure. Therefore, clinical intracranial pressure (Intracranial Pressure, ICP) monitoring is very important. It is the basis for preventing and controlling intracranial hypertension and determining the treatment plan. It also provides an o...

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Problems solved by technology

[0003] However, at present, the non-invasive monitoring of intracranial pressure is still a worldwide problem. Although there are many patents and documents on non-invasive monitoring of intracranial pressure at home and abroad, there are no mature products certified by the US FDA and European CE. The prospect is bright; although there are two non-invasive detection analyzers for intracranial pressure based on flash visual evoked potentials in China, since these two instruments are based on a single non-invasive detection method for intracranial pressure, there is inevitably a single intracranial pressure Principle flaws of non-invasive testing methods

Moreover, the prior art also has the following deficiencies: (a) the signal processing method is relatively simple, the repeatability of the instrument is not high, and manual intervention is required to diagnose the results; (c) the openness of the instrument is not enough, and the information management and communication capabilities are weak; (d) the shortcomings of the existing methods in the non-invasive monitoring of intracranial pressure are not that they have not found the relevant cranial pressure. variables related to intracranial pressure, but in the absence of a data processing device to calibrate these variables to obtain the true waveform value of intracranial pressure

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