Test bed for realizing fuse of nuclear magnetic resonance imaging and in-vivo visible light three-dimensional imaging of animal

A nuclear magnetic resonance image and three-dimensional image technology, applied in the fields of application, medical science, sensors, etc., can solve the problem of high cost of fluorescent labeling, and achieve the effect of low cost, high spatial resolution, and accurate spatial positioning

Inactive Publication Date: 2012-05-09
NANJING UNIV OF AERONAUTICS & ASTRONAUTICS
View PDF2 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The fusion of NMR images and in vivo visible light images theoretically requires dual-labeled probes that can be imaged in NMR systems and visualized in in vivo visible light imaging systems. The cost of labeling is also very expensive (up to several thousand yuan per milliliter)

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Test bed for realizing fuse of nuclear magnetic resonance imaging and in-vivo visible light three-dimensional imaging of animal
  • Test bed for realizing fuse of nuclear magnetic resonance imaging and in-vivo visible light three-dimensional imaging of animal
  • Test bed for realizing fuse of nuclear magnetic resonance imaging and in-vivo visible light three-dimensional imaging of animal

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0014] The present invention will be described in detail below in conjunction with the accompanying drawings.

[0015] Such as figure 1 , figure 2 , image 3 As shown, the main body of the present invention is an experimental bed 1 for carrying small animals, and the material is plexiglass. Can be mounted seamlessly on the small animal NMR vibrating bed without compromising the centering of the small animal relative to the coil.

[0016] There are four marker holes 2, 3, 4, and 5 on the bed body, and nuclear magnetic resonance markers are encapsulated in the holes, so that the four marker holes can be imaged in small animal nuclear magnetic resonance, and the nuclear magnetic resonance markers used will not affect small animals. Signal.

[0017] 6 is a series of small diameter holes, which are used as penetration holes for transmitting fluorescent excitation light. In order to avoid the light path change caused by directly penetrating the plexiglass.

[0018] 7,8,9,10,1...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a test bed for realizing fuse of a nuclear magnetic resonance imaging and an in-vivo visible light three-dimensional image of an animal. The test bed comprises a test bed body and an animal fixing device arranged on the test bed body, the test bed body is provided with a marker hole on which a nuclear magnetic resonance imaging marker is packaged, and the test bed body is also provided with a penetrating hole for fluorescence transmission and three-dimensional imaging. According to the invention, the marker on the marker hole can be captured by a nuclear magnetic resonance imaging system and an in-vivo visible light three-dimensional imaging system, and thus the fuse of a nuclear magnetic resonance imaging and an in-vivo visible light three-dimensional image of an animal can be realized.

Description

technical field [0001] The invention relates to a small animal experimental bed, which is used for the fusion of nuclear magnetic resonance images of small animals and three-dimensional visible light images in vivo. Background technique [0002] Bioluminescence imaging (bioluminescence) and fluorescence imaging (fluorescence) are emerging visible light imaging technologies in vivo in recent years. It can non-destructively and real-time monitor the activities and responses of labeled cell tissues in small living animals, and has great application potential in tumor detection, gene expression, protein molecular detection, drug receptor localization, drug screening and drug efficacy evaluation, etc. With the continuous development of imaging technology and detection instruments, it has gradually developed from plane two-dimensional imaging to three-dimensional three-dimensional imaging. Three-dimensional imaging technology has made great progress in the spatial positioning...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61B19/00A61B5/055A61B5/00A61B90/00
Inventor 陈春晓王睿杨伟吴佳妮滕皋军
Owner NANJING UNIV OF AERONAUTICS & ASTRONAUTICS
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap