Application of multinoside to preparing anti-hypoxia medicament
An anti-hypoxic drug, the technology of rosin, which is applied in the direction of drug combination, anti-drug, pharmaceutical formula, etc., can solve the problems of few studies on the pharmacological activity of rosin, achieve good clinical application prospects, improve survival time, and significantly protective effect
Inactive Publication Date: 2013-03-06
LOGISTICS UNIV OF CAPF
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- Abstract
- Description
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- Application Information
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Problems solved by technology
[0005] Rosaside is a triterpenoid component in Rosaceae plants, with a sterol glycoside structure. At present, there are very few studies on the pharmacological activity of rosin, and there is no research report on its anti-hypoxic activity.
Method used
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Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0062] Tablets made from Rosaside
[0063]
[0064] The above formula is made into tablets according to traditional processing methods.
Embodiment 2
[0066] Capsules made from Rosaside
[0067] Rosaside 20mg
[0068] Starch 70mg
[0069] Prepared according to the traditional pharmaceutical process, put into No. 2 capsules.
Embodiment 3
[0071] Oral syrup made from Rosaside:
[0072]
[0073]
[0074] Add the above components into water to adjust to the required amount, mix well and bottle.
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Provided is the use of multiflora glycoside in preparing an anti-hypoxic drug. A full body and cell level hypoxia model indicates that multiflora glycoside can significantly increase the survival time of a mouse with asphyxiant hypoxia, and has a significant protection effect on endothelial cell injury induced by hypoxia.
Description
technical field [0001] The present invention relates to the application of a pharmaceutical product, in particular to the application of rosin in the preparation of anti-hypoxic drugs. Background technique: [0002] Oxygen is an important condition for the survival of human beings and many organisms. When the oxygen required by the body's vital activities cannot be supplied adequately, it is called hypoxia or hypoxia. Hypoxia will cause abnormal changes in body metabolism, function, and even morphological structure. Severe or long-term hypoxia will bring serious harm to the body, and eventually lead to the death of important organs such as the heart and brain due to insufficient energy supply. Oxygen and hypoxia are important topics in the basic theory of life sciences. The formation of hypoxia can be divided into three categories: the first category is the reduction of oxygen content in the external environment, which makes it impossible to take in enough oxygen during n...
Claims
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IPC IPC(8): A61K31/7024A61P39/06
CPCA61K31/56A61K9/4866A61K9/0095A61K36/738A61K31/7024A61K36/73A61K9/2059A61P9/00A61P39/06
Inventor 李灵芝张永亮龚海英王越顾军郭鹏段晓彦王舒
Owner LOGISTICS UNIV OF CAPF