Micro mixing and micro reaction device

A micro-reaction device and micro-mixing technology, applied in mixers, chemical instruments and methods, and laboratory containers, can solve problems such as high cost, difficult processing, and singleness, and achieve convenient connection, improved mixing efficiency, and The effect of broad application prospects

Active Publication Date: 2012-07-04
HUAZHONG UNIV OF SCI & TECH
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] Aiming at the defects of single mixing mechanism, limited time resolution, high processing difficulty, expensive processing equipment and high cost of the existing micro-mixer, the present invention provides a micro-mixing and micro-reaction device, through the "cross micro

Method used

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  • Micro mixing and micro reaction device
  • Micro mixing and micro reaction device

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Embodiment Construction

[0038] The present invention will be described in detail below in conjunction with the accompanying drawings and embodiments.

[0039] In this embodiment, the micro-mixing and micro-reaction device consists of two parts: a microfluidic chip and a chip clip.

[0040] Such as Figure 1-2 As shown, the microfluidic chip is a polydimethylsiloxane (PDMS) microfluidic chip, which is formed by bonding a thin layer of polydimethylsiloxane (PDMS) with a microchannel structure and a glass sheet .

[0041] The microchannel structure in the PDMS thin layer is three connected channels, such as figure 2 shown. It includes two inlet passages and one outlet passage, and the two inlet passages and one outlet passage communicate through the mixing chamber 4 .

[0042]In the present embodiment, the angle of the central axes of the two inlet passages is 90 degrees, and the solutions are respectively from the inlet passage reservoirs 1 and 10 (the inlet passage reservoirs in this embodiment a...

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Abstract

The invention discloses a micro mixing and micro reaction device, which is used for realizing the fast micro mixing and micro reaction of solution and comprises a micro flow control chip and a chip clamp, wherein the micro flow control chip is formed by bonding a polydimethylsiloxane (PDMS) thin layer carved with a micro passage with a glass sheet, and the chip clamp is used for clamping the micro flow control chip. The micro mixing and micro reaction device is characterized in that the micro flow passage comprises two solution inlet passages and one solution outlet passage, each passage is formed by communicating and connecting a wide passage with a narrow passage, and in addition, the three narrow passages are respectively communicated and connected with a mixing cavity (4), so the three passages are mutually communicated. The micro mixing and micro reaction device has the advantages that the processing is simple, the cost is low, in addition, good optical and mechanical performance and insulation performance are realized, in addition, the micro mixing and micro reaction device can be conveniently connected and integrated with external equipment, a new path is provided for the super fast micro mixing of the solution, and the micro mixing and micro reaction device can be widely applied to the field of super fast micro reaction dynamics study.

Description

technical field [0001] The invention relates to a micro-mixing and micro-reaction device, which can realize ultra-fast mixing at the submicrosecond level, provides a way for ultra-fast micro-mixing of solutions, and is widely used in the field of ultra-fast micro-reaction kinetics research. Background technique [0002] Microfluidic chip (Microfluidic chip), also known as Lab-on-a-chip (Lab-on-a-chip) or Micro-Total Analysis System (μTAS), uses micro-processing technology to pretreat samples involved in chemistry , reaction, separation, detection, cell culture, sorting, lysis and other basic operation units involved in life sciences are integrated on a chip of a few square centimeters in size. Or the various functions of the biological laboratory. Since Manz et al. (Manz, A., Graber, N.and Widmer, H.M. (1990) Miniaturized Total Chemical-Analysis Systems-a Novel Concept for Chemical Sensing.Sensor.Actuat.B-Chem. in the early 1990s., 1 , 244-248) first proposed the concept o...

Claims

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Application Information

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IPC IPC(8): B01F13/00B01J19/00B01L3/00
Inventor 刘笔锋徐友志冯晓均李颖
Owner HUAZHONG UNIV OF SCI & TECH
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