Diffuse optical tomography system based on electron multiplication CCD (charge-coupled device) and tomography method

A technology of electron multiplication and imaging system, which is applied in the field of diffuse optical tomography, can solve the problems of not involving the diffusion angle of propagation and insufficient spatial resolution, etc., and achieve the goal of eliminating coupling factors, increasing spatial sampling rate, improving efficiency and accuracy Effect

Inactive Publication Date: 2012-07-18
TIANJIN UNIV
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Problems solved by technology

[0005] Although various research groups at home and abroad are committed to improving the imaging quality and computational efficiency of DOT, the main problem of DOT technology is still the lack of spatial resolution due to the high scattering of near-infrared light by the tissue.
Moreover, there are more and mo

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  • Diffuse optical tomography system based on electron multiplication CCD (charge-coupled device) and tomography method
  • Diffuse optical tomography system based on electron multiplication CCD (charge-coupled device) and tomography method
  • Diffuse optical tomography system based on electron multiplication CCD (charge-coupled device) and tomography method

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Embodiment Construction

[0032] The invention is a non-contact DOT measuring system, which adopts a space scanning light source and uses an electron multiplying CCD as a detector. By increasing the number of light sources and detectors, the spatial sampling rate is increased, thereby improving the spatial resolution of imaging. Based on this system, a large amount of measurement information can be obtained, and the imaging quality of the reconstructed image can be improved.

[0033] The system structure of the present invention is as figure 1 As shown, it is mainly composed of a light source 1, an electric control box 2, a translation platform 3, a coupling lens 4, a phantom body 5, a lens 6, a CCD 7 and a computer 8.

[0034] The steady-state laser with a wavelength of 785nm emitted by the light source is transmitted to the translation stage through the incident optical fiber (core diameter is 500μm). The translation table moves up and down to drive the optical fiber head to move, so that the laser...

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Abstract

The invention belongs to the technical field of physiological parameter measurement, and relates to a diffuse optical tomography system based on an electron multiplication CCD (charge-coupled device), which comprises a steady-state laser source, a translation stage, a coupling lens, a lens, the electron multiplication CCD and a computer. Steady-state laser emitted by the steady-state laser sourceirradiates a phantom or an object to be measured through incident optical fibers, the translation stage drives an optical fiber head to move so that the laser irradiates various imaging points of thephantom, afterwards, the lens receives transmission light emitted from the phantom to form an image in the electron multiplication CCD, imaging results are transmitted to the computer, and the computer reconstructs the image. The invention further provides a tomography method implemented by using the system. The imaging quality of the reconstructed image can be improved, underdetermined ill-posednature of imaging algorithm is eliminated at the utmost, and image reconstruction efficiency and precision are improved.

Description

field of invention [0001] The invention belongs to the technical field of physiological parameter measurement, in particular to the application of diffusion optical tomography technology, Background technique [0002] Diffuse Optical Tomography (DOT) technology uses near-infrared light to irradiate the tissue body, detects the diffuse light emitted through the tissue body, and obtains the distribution image of the optical parameters of the human tissue, and infers the tissue density from these optical parameters. Physiological conditions and lesion information, and then realize the diagnosis of diseases. Diffusion optical tomography has the characteristics of non-invasive, safe, non-ionizing radiation and high specificity, and is useful in the early diagnosis of breast tumors. [1-3] , functional brain imaging [4，5] and small animal imaging [6，7] It has great potential for practical application. [0003] However, compared with other mature imaging methods (such as CT, MRI...

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Application Information

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IPC IPC(8): A61B5/00G01N21/35
Inventor 赵会娟周晓青侯强范颖高峰
Owner TIANJIN UNIV
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