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Application of Chinese medicinal composition in preparing medicament for preventing and treating Parkinsonism

A Parkinson's disease and composition technology, applied in the field of traditional Chinese medicine composition, can solve the problems of insufficient disclosure of the drug composition and proportion of Bushen Huoxue Granules, safety and reliability of traditional Chinese medicine prevention, and large side effects of western medicine prevention, achieving good application prospects and effects Obvious, less medicinal effect

Inactive Publication Date: 2013-11-20
XIN HUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the side effects of western medicine prevention are relatively large, and it is not as safe and reliable as traditional Chinese medicine prevention.
my country has accumulated rich experience in the prevention of PD with traditional Chinese medicine, summarizing its prevention principles: the method of benefiting qi and activating blood, the method of nourishing yin and suppressing yang, the method of calming the liver and extinguishing wind, the method of kneading tendons and extinguishing wind, the method of promoting blood circulation and removing blood stasis, and the method of dredging collaterals and extinguishing wind. , there are also many kinds of Chinese medicine compositions for preventing PD, but there are few Chinese medicine compositions for preventing PD motor complications, such as the Chinese journal "Chinese Journal of Traditional Chinese Medicine", June 2011, Volume 26, No. 6, published The "Clinical Study on the Prevention of Parkinson's Disease Motor Complications with Bushen Huoxue Granules" disclosed that Bushen Huoxue Granules can improve the symptoms of motor complications in PD patients, but did not fully disclose the drug composition and ratio of the aforementioned Bushen Huoxue Granules
Therefore, it is necessary to actively explore safe and reliable drugs that can effectively prevent motor complications of Parkinson's disease, but there are no reports about such drugs

Method used

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  • Application of Chinese medicinal composition in preparing medicament for preventing and treating Parkinsonism
  • Application of Chinese medicinal composition in preparing medicament for preventing and treating Parkinsonism
  • Application of Chinese medicinal composition in preparing medicament for preventing and treating Parkinsonism

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Example 1 Preparation of traditional Chinese medicine composition for preventing Parkinson's disease (1)

[0030] 10 parts of Gastrodia elata, 20 parts of astragalus, 15 parts of Rehmannia glutinosa, 25 parts of white peony, 15 parts of angelica, 20 parts of Uncaria, 7 parts of silkworm, 13 parts of Aracea, decocted in conventional methods.

Embodiment 2

[0031] Example 2 Preparation of traditional Chinese medicine composition for preventing Parkinson's disease (2)

[0032] 20 parts of Gastrodia elata, 10 parts of astragalus, 25 parts of Rehmannia glutinosa, 15 parts of white peony, 25 parts of angelica, 10 parts of Uncaria, 13 parts of silkworm, 7 parts of Aracea, decocted in conventional methods.

Embodiment 3

[0033] Example 3 Preparation of traditional Chinese medicine composition for preventing Parkinson's disease (3)

[0034] 10 parts of Gastrodia elata, 10 parts of astragalus, 25 parts of Rehmannia glutinosa, 25 parts of white peony, 15 parts of angelica, 10 parts of Uncaria, 13 parts of silkworm, 13 parts of Aracea, decocted in conventional methods.

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Abstract

The invention relates to application of a Chinese medicinal composition in preparing a medicament for preventing and treating Parkinsonism. The Chinese medicinal composition is prepared from the following bulk pharmaceutical chemicals in parts by weight: 10 to 20 parts of gastrodia elata, 10 to 20 parts of astragalus mongholicus, 15 to 25 parts of prepared rehmannia root, 15 to 25 parts of white peony root, 15 to 25 parts of Chinese angelica, 10 to 20 parts of uncaria, 7 to 13 parts of stiff silkworm, and 7 to 13 parts of rhizoma arisaematis. The invention has the following advantages: the compatibility of Chinese medicinal composition is in accordance with the principle of 'monarch, minister, assistant and guide' of Chinese medicaments, treatment is started from the pathogen fundamentally, and the Chinese medicament is applied according to symptoms and has an exact curative effect in assisting and preventing the Parkinsonism; the Chinese medicinal composition for preventing the Parkinsonism has the advantages of no toxic or side effect, low price and the like, and is easily accepted by patients; and the Chinese medicinal composition has few drugs, rich raw materials, simple preparation process, environmental friendliness, and excellent application prospect in preventing the Parkinsonism.

Description

technical field [0001] The invention relates to the use of a traditional Chinese medicine composition, in particular to the application of a traditional Chinese medicine composition in the preparation of drugs for preventing Parkinson's disease. Background technique [0002] Parkinson's disease (PD) is a common neurodegenerative disorder in middle-aged and elderly people, which is mainly related to the degeneration and loss of dopaminergic neurons in the substantia nigra compact area and the resulting reduction of dopamine transmitters in the nigrostriatal pathway. Traditional Chinese medicine believes that PD is a "tremor syndrome", which mostly occurs in middle-aged and elderly people when "Tiangui" is exhausted. The exhaustion of "Tiangui" indicates the lack of kidney essence, the deficiency of Rongwei, the upper part does not nourish the liver and wood, the outer part does not moisten the tendons, and the water does not contain wood. Then yin deficiency and yang hyperact...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8988A61P25/16A61K35/64
Inventor 刘振国魏江磊吴娜陈伟袁伟恩
Owner XIN HUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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