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Drug combination for treating dysthymic disorder

A technology for depression and composition, applied in the field of psychiatric prevention and treatment, can solve problems such as large side effects and strong dependence, and achieve the effects of no side effects, reasonable formula and significant curative effect

Active Publication Date: 2012-09-12
溧阳市上黄镇卫生院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the clinical treatment is mainly based on western medicine, but its side effects are relatively large and the dependence is strong, which brings more hidden dangers while treating patients.

Method used

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  • Drug combination for treating dysthymic disorder
  • Drug combination for treating dysthymic disorder
  • Drug combination for treating dysthymic disorder

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] The preparation of embodiment 1 tablet

[0014] Take 500 grams of Uncaria chinensis, 300 grams of schisandra, 2000 grams of medlar, 500 grams of turmeric, 2000 grams of Albizia bark, 500 grams of Tribulus terrestris, 300 grams of Poria cocos, 1000 grams of jujube seed, 1500 grams of white peony root, 300 grams of gardenia, and Shichangpu 1500 grams, 300 grams of Chonglou, 1000 grams of Gastrodia elata, 300 grams of Acanthopanax, 300 grams of woody incense, pulverized by a pulverizer, passed through a 80 mesh sieve, added 3000 grams of microcrystalline cellulose, 1000 grams of mannitol, mixed evenly, and used 10 The starch aqueous solution in % by weight is granulated, and after drying, it is mixed evenly with 500 grams of cross-linked polyvinylpyrrolidone, and pressed into 1000 tablets.

experiment example

[0016] Diagnostic criteria

[0017] According to the "International Classification of Diseases - Tenth Edition" published by WHO, the "Diagnostic and Statistical Manual of Mental Disorders - Fourth Edition" of the American Psychiatric Association and the third edition of China Classification and Diagnostic Criteria for Mental Disorders (CCMD-3) on the diagnostic criteria for depression To diagnose mental depression and exclude organic diseases. The degree of depression was scored according to the Hamilton Depression Rating Scale (HAMD) (24 items in total), of which 24 was classified as severe depression. For HAMD scores, see "Psychiatric Evaluation Scale" [M]. Changsha: Hunan Science and Technology Press, 1993, pp. 122-203.

[0018] Selected 60 patients who met the above criteria, including 30 males and 30 females; aged 29 to 57 years, with an average of 41 years old.

[0019] Use the tablet that makes among the embodiment 1 to carry out treatment, wherein 3 times a day, eac...

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Abstract

The invention relates to a drug combination for treating dysthymic disorder.. The drug combination is prepared by uncaria, Chinese magnoliavine fruit, barbary wolfberry fruit, radix curcumae, cortex albiziae, caltrop, poria cocos, spina date seed, white paeony root, gardenia, acorus gramineus, rhizoma paridis, rhizoma gastrodiae, medofenoxate and costus root. The drug combination for treating thedysthymic disorder, disclosed by the invention, has the advantages of simpleness in component, easiness in obtaining the component, significant curative effect and no obvious side effect.

Description

technical field [0001] The invention relates to the field of mental illness prevention and treatment, in particular, the invention relates to a pharmaceutical composition for treating mental depression. Background technique [0002] Mental depression is a class of neurotic disorders that are easily excitable and mentally fatigued, often have emotional troubles and psychophysiological symptoms. Twenty-five percent of depressed patients treated in hospitals are mentally depressed. In addition to the symptoms of general depression, mental depression also has its own characteristics, such as hallucinations and delusions. [0003] At present, the clinical treatment is mainly based on western medicine, but its side effects are relatively large and the dependence is strong, which brings more hidden dangers while treating patients. Contents of the invention [0004] The object of the present invention is to provide a pharmaceutical composition for treating mental depression. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P25/24
Inventor 高新华
Owner 溧阳市上黄镇卫生院
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