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Compound acne-removal cream and production method thereof

A production method and a technology for compound acne, which are applied in the directions of ointment delivery, pharmaceutical formulation, emulsion delivery, etc., can solve problems such as poor curative effect and inability to completely cure acne, and achieve the effect of convenient use.

Active Publication Date: 2013-10-30
甘肃省商业科技研究所有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] But the curative effect of above-mentioned medicine is bad, all can not cure acne completely

Method used

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  • Compound acne-removal cream and production method thereof
  • Compound acne-removal cream and production method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0137] Take the same quality mugwort, angelica, calamus, atractylodes, cortex, coix seed, pepper, coptis and licorice, mix and grind them to make a medicinal powder, put the medicinal powder into a multifunctional extraction tank, and add 5 times the total mass of the medicinal powder Heat the water while stirring, reflux and extract at 90°C for 60 minutes, stop heating, filter the extract to obtain the first supernatant; , at the same temperature as the first extraction, reflux extraction for the same time, filter the extract to obtain the second supernatant; send the first supernatant and the second supernatant to the concentration tank, and Heating while stirring, and concentrating under reduced pressure at a temperature of 80°C. During the process of concentrating under reduced pressure, turn on the vacuum pump while concentrating and reducing pressure, so that the vacuum degree is finally kept at 300mmHg, and a concentrated solution with a mass fraction of solid content of...

Embodiment 2

[0146] Take the same quality mugwort, angelica, calamus, atractylodes, cortex, coix seed, pepper, coptis and licorice, mix and grind them to make a medicinal powder, put the medicinal powder into a multifunctional extraction tank, and add 5 times the total mass of the medicinal powder Heat the water while stirring, reflux extraction at a temperature of 95°C for 45 minutes, stop heating, filter the extract to obtain the first supernatant; , at the same temperature as the first extraction, reflux extraction for the same time, filter the extract to obtain the second supernatant; send the first supernatant and the second supernatant to the concentration tank, and Heating while stirring, and concentrating under reduced pressure at a temperature of 100°C. During the process of concentrating under reduced pressure, turn on the vacuum pump while concentrating and reducing pressure, so that the vacuum degree is finally kept at 750mmHg, and a concentrated solution with a mass fraction of...

Embodiment 3

[0148] Take the same quality mugwort, angelica, calamus, atractylodes, cortex, coix seed, pepper, coptis and licorice, mix and grind them to make a medicinal powder, put the medicinal powder into a multifunctional extraction tank, and add 5 times the total mass of the medicinal powder Heat the water while stirring, reflux extraction at a temperature of 100°C for 30 minutes, stop heating, filter the extract to obtain the first supernatant; , at the same temperature as the first extraction, reflux extraction for the same time, filter the extract to obtain the second supernatant; send the first supernatant and the second supernatant to the concentration tank, and Heating while stirring, and concentrating under reduced pressure at a temperature of 90°C. During the process of concentrating under reduced pressure, turn on the vacuum pump while concentrating and reducing pressure, so that the vacuum degree is finally kept at 525mmHg, and a concentrated solution with a mass fraction of...

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Abstract

The invention discloses compound acne-removal cream and a production method thereof. The production method comprises the following steps of mixing and grinding artemisia argyi, radix angelicae, calamus, rhizoma atractylodis, golden cypress, semen coicis, pepper, coptis chinensis and liquorice which are equal in mass, and performing reflux extraction for two times; performing reduced-pressure concentration and spray drying on supernate; concentrating into the cream after the extraction is performed for two times; drying and grinding; and meanwhile, preparing a base material; adding ground medicine powder to the base material; performing shear emulsification; filtering; and naturally cooling filtrate to room temperature to produce the compound acne-removal cream. By taking traditional Chinese medicines as raw materials, the acne-removal cream has the targeted curative effect on acnes, can play a role of restraining and treating symptoms of male and female acne patients of all ages and can be used for completely curing the acnes, and great convenience is brought to use of vast patients.

Description

technical field [0001] The invention belongs to the technical field of medicinal chemistry, and relates to a compound cream for external use comprising extracts of traditional Chinese medicines and biosynthetic raw materials, in particular to a compound acne clear cream; the invention also relates to a production method of the cream. Background technique [0002] According to reports: there are nearly 300 million acne patients in my country, among which the incidence rate of adolescents aged 11-25 is over 80%, and the incidence rate of youth aged 26-35 is over 15%; the younger one is 11 years old, and the older one is about 45 years old 21% were men, 79% were women; 24.5% were married, 75.5% were unmarried; more than 68% of acne patients neglected treatment, and 32% of patients believed that they should be treated in time. [0003] There are many types of medicines for treating acne, and the ones currently used clinically are: [0004] 1) External creams: 20% azelaic acid cr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8994A61K9/06A61P17/10A61K31/496A61K31/4174
Inventor 牛犇梁宁丁洁
Owner 甘肃省商业科技研究所有限公司
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