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Chinese materia medica preparation for treating leukocytopenia and preparation process thereof

A technology of leukopenia and traditional Chinese medicine, applied in the field of medicine, can solve problems such as inability to form large-scale industrial production, failure to obtain special review, shortage of resources, etc., and achieve the effect of convenient application, no toxic side effects, and reduced appetite

Inactive Publication Date: 2012-10-31
河南天方药业中药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above traditional Chinese medicines and extracts have not undergone comprehensive, systematic, and strict pharmaceutical research, or are short of resources, and have not obtained special national review, and cannot form large-scale industrial production, which limits their application.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Example 1 Granule formulation

[0020] Astragalus 310g Angelica 620g Ligustrum lucidum 206g Cortislava 200g

[0021] Chinese wolfberry 310g psoralen 150g danshen 110g aconite 162g

[0022] For the above eight flavors, take Angelica sinensis and Ligustrum lucidum and extract 8 times the amount of ethanol and reflux twice for 1.5 hours each time. Combine the extracts and filter. The filtrate recovers the ethanol and concentrates under reduced pressure to a relative density of 1.30 to 1.35 (60°C). spare. Combine the medicinal residue with Astragalus and Chinese wolfberry, add 8 times the amount of water to decoct twice, the first time is 2 hours, the second time is 1.5 hours, combine the decoction, filter; Caulis spatholobi, Psoralen, Salvia, Monkshood Combine, add 8 times the amount of water and cook twice, the first time is 2 hours, the second time is 1.5 hours, combine the decoction, filter, the filtrate is concentrated to a relative density of about 1.08 (90 ℃), pl...

Embodiment 2

[0023] Example 2 Pellets formulation

[0024] Astragalus 310g, Angelica 620g Ligustrum lucidum 206g Caulis spatholobi 200g

[0025] Chinese wolfberry 310g psoralen 150g danshen 110g aconite 162g

[0026] For the above eight flavors, take Angelica sinensis and Ligustrum lucidum and extract 8 times the amount of ethanol and reflux twice for 1.5 hours each time. Combine the extracts and filter. The filtrate recovers the ethanol and concentrates under reduced pressure to a relative density of 1.30 to 1.35 (60°C). spare. Combine the medicinal residue with Astragalus and Chinese wolfberry, add 8 times the amount of water to decoct twice, the first time is 2 hours, the second time is 1.5 hours, combine the decoction, filter; Caulis spatholobi, Psoralen, Salvia, Monkshood Combine, add 8 times the amount of water and cook twice, the first time is 2 hours, the second time is 1.5 hours, combine the decoction, filter, the filtrate is concentrated to a relative density of about ...

Embodiment 3

[0027] Example 3 Capsule preparation

[0028] Astragalus 310g, Angelica 620g Ligustrum lucidum 206g Caulis spatholobi 200g

[0029] Chinese wolfberry 310g psoralen 150g danshen 110g aconite 162g

[0030] For the above eight flavors, take Angelica sinensis and Ligustrum lucidum and extract 8 times the amount of ethanol and reflux twice for 1.5 hours each time. Combine the extracts and filter. The filtrate recovers the ethanol and concentrates under reduced pressure to a relative density of 1.30 to 1.35 (60°C). spare. Combine the medicinal residue with Astragalus and Chinese wolfberry, add 8 times the amount of water to decoct twice, the first time is 2 hours, the second time is 1.5 hours, combine the decoction, filter; Caulis spatholobi, Psoralen, Salvia, Monkshood Combine, add 8 times the amount of water and cook twice, the first time is 2 hours, the second time is 1.5 hours, combine the decoction, filter, the filtrate is concentrated to a relative density of about 1.08...

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PUM

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Abstract

The invention discloses a Chinese materia medica preparation for treating leukocytopenia and a preparation process thereof and belongs to the technical field of drugs. The Chinese materia medica preparation is prepared by the following raw materials, by weight, of 10-40% of astragalus mongholicus, 5-40% of angelica sinensis, 5-30% of fructus ligustri lucidi, 5-30% of caulis spatholobi, 5-30% of the root of red-rooted salvia, 5-30% of monkshood, 5-30% of the fruit of Chinese wolfberry and 5-30% of fructus psoraleae. Raw medicinal materials of the Chinese materia medica preparation is a pure Chinese materia medica preparation, clinical market effects are obvious and safe, and pharmacodynamic effects of the leukocytopenia caused by radiotherapy and chemotherapy of tumour patients are obvious. The Chinese materia medica preparation is simple in process, stable in quality, controllable in cost and suitable to industrial production.

Description

Technical field [0001] The invention belongs to the technical field of medicine, and relates to a traditional Chinese medicine preparation that nourishes the liver and kidney, replenishes qi and promotes blood, and can treat tumor patients with leukopenia caused by radiotherapy and chemotherapy. Background technique [0002] Leukopenia refers to the patient's peripheral blood white blood cell count below 4×10 9 / L, is one of the most common complications of chemotherapy, clinically manifested as fatigue, dizziness, insomnia, weakness in waist and knees, cold limbs, pale tongue, white fur, weak pulse and other symptoms. The clinical symptoms are In the category of "deficiency tuberculosis" in Chinese medicine, patients have reduced disease resistance, are vulnerable to infection, and affect the completion of chemotherapy. [0003] Studies based on theories of clinical pharmacology have shown that most of the curative effects of chemotherapy and radiotherapy are currently dose-relate...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61P7/00
Inventor 张新琴王和平武香香李书德
Owner 河南天方药业中药有限公司
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