Interleukin 21 (IL-21) medicine for cancer therapy

An interleukin and tumor technology, applied in anti-tumor drugs, drug combinations, pharmaceutical formulations, etc., can solve problems such as unsatisfactory tumor treatment effects, and achieve the effects of preventing tumor recurrence, improving microenvironment, and enhancing curative effects.
CN102775501AActive Publication Date: 2012-11-14乘典(苏州)生物医药有限公司
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
乘典(苏州)生物医药有限公司
Publication Date
2012-11-14

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Abstract

The invention relates to the field of cancer therapy and relates to fusion protein of interleukin 21 and an anti-Her2 / neu single-chain antibody, wherein the fusion protein is utilized to treat breast cancer.
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Description

technical field

[0001] The present invention relates to the field of tumor treatment. In particular, the invention relates to the use of interleukin-21 in the treatment of tumors. More specifically, the present invention relates to the treatment of breast cancer using a fusion protein of interleukin 21 and an anti-Her2 / neu single chain antibody. Background technique

[0002] The body's immunity plays an important role in the occurrence and development of tumors. In recent years, studies have found that the body's anti-tumor immune response also plays an important role in the therapeutic effects of conventional tumor radiotherapy and chemotherapy. Tumor radiotherapy and chemotherapy lead to massive death of tumor cells, release tumor antigens and a series of "danger signals", activate the body's innate immune signaling pathway, promote the uptake, processing and presentation of antigens by antigen-presenting cells, and induce and enhance the body's anti-tumor immune response...

Claims

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