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Traditional Chinese medicine composition for treating gastroesophageal reflux disease and preparation method

A gastroesophageal reflux and composition technology, applied in the direction of drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve problems that cannot be solved fundamentally, and achieve the goal of improving credibility and evidence level Effect

Inactive Publication Date: 2013-01-09
XIYUAN HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these drug treatments cannot fundamentally solve the problem. For details, see the article "Analysis of the Clinical Observation of Gastroesophageal Reflux Disease Treated by Integrated Traditional Chinese and Western Medicine in my country" by Zhao Yingpan et al. (Chinese Journal of Integrative Traditional Chinese and Western Medicine, 2009, 29 (9): 860-864)

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Example 1 Preparation of Tongjiang Granules, a Traditional Chinese Medicine Composition for the Treatment of Gastroesophageal Reflux Disease

[0018] 1) Weigh 300 grams Cyperus Cyperi, 300 grams Perilla Stem, 225 grams Tangerine Peel, 250 grams Coptidis Rhizoma, 750 grams Cuttlefish Bone, 225 grams Polygonum cuspidatum, 50 grams Evodia and 75 grams Licorice;

[0019] 2) Decoct the medicinal material with water for 2-3 times, combine the medicinal liquid, filter, concentrate the filtrate into a paste, add sucrose and dextrin according to the ratio of clear paste: sugar powder: dextrin of 1:3:1, and prepare Granules, dried to get Tongjiang granules.

Embodiment 2

[0020] Embodiment 2: the preparation of decoction

[0021] 1) Weigh 120 grams of Rhizoma Cyperi, 120 grams of Perilla Stem, 80 grams of Tangerine Peel, 60 grams of Coptidis Rhizoma, 200 grams of Cuttlefish Bone, 80 grams of Polygonum cuspidatum, 20 grams of Evodia rutaecarpa and 30 grams of Licorice;

[0022] 2) Add water to decoct the medicinal material for 2-3 times, combine the medicinal liquid, filter and concentrate to obtain a decoction.

Embodiment 3

[0023] Embodiment 3: the preparation of capsule

[0024] 1) Weigh 150 grams Cyperus Cyperi, 150 grams perilla stalk, 120 grams tangerine peel, 120 grams Coptis chinensis, 40 grams Evodia rutaecarpa, 300 grams squid bone, 120 grams Polygonum cuspidatum and 100 grams licorice;

[0025] 2) Crush the medicinal material, decoct it with water for 2-3 times, combine the medicinal liquid, filter, concentrate the filtrate into a thick paste, dry it, grind it into a fine powder, and pack it into a capsule.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating gastroesophageal reflux disease, which comprises the following raw materials such as Cyperus Rotundus L, Perilla Stem, dried orange peel, coptis, evodia, cuttlefish bone, gentrin knotweed and licorice, and various oral dosage forms can be prepared by adding pharmaceutically used auxiliary materials. The traditional Chinese medicine composition is prepared to a preparation by an internal medicine of a hospital, according to the clinic usage, the improved symptom has substantial curative effect. The invention also discloses a preparation method of the composition.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating liver-stomach disharmony type gastroesophageal reflux disease, and also relates to a preparation method of the composition. Background technique [0002] Gastroesophageal reflux disease (GERD) is the reflux of gastric and duodenal contents into the human esophagus, causing heartburn and other symptoms, and can cause reflux esophagitis (RE), as well as throat, airway and other esophagus. tissue damage. GERD is a common disease in gastroenterology outpatient clinics. It recurs and seriously affects the quality of life of patients. With the increasing pressure of work and life in modern society, the incidence of GERD has also increased. At present, drugs that inhibit gastric acid include proton pump inhibitors (PPI) and H2 receptor antagonists. Commonly used are omeprazole, lansoprazole, esomeprazole, ranitidine, etc., and their mechanisms of action are Suppress stomach ac...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61K36/8966A61K36/9064A61K36/9066A61P1/04A61K35/56A61K35/618
Inventor 唐旭东李保双吴红梅李振华王凤云王萍吴丹明卞立群赵迎盼张丽颖宋秀江钟民冯月香刘珊
Owner XIYUAN HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI