Unlock instant, AI-driven research and patent intelligence for your innovation.

An effective part of Atractylodes macrocephala for treating constipation of spleen deficiency type

A technology of spleen deficiency type and Atractylodes macrocephala, applied in the field of effective parts of Atractylodes macrocephala for treating spleen deficiency type constipation

Active Publication Date: 2019-10-11
ZHEJIANG FORESTRY UNIVERSITY
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Atractylodes glycoconjugate, extracted from Atractylodes macrocephala, has strong biological activity and has the effect of lowering blood sugar, but there is no report on its application in the treatment of spleen-deficiency constipation

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • An effective part of Atractylodes macrocephala for treating constipation of spleen deficiency type
  • An effective part of Atractylodes macrocephala for treating constipation of spleen deficiency type
  • An effective part of Atractylodes macrocephala for treating constipation of spleen deficiency type

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0085] Example 1: Extraction method of the effective parts of Atractylodes macrocephala treating spleen-deficiency type constipation

[0086] (1) Take an appropriate amount of the original medicinal material Atractylodes macrocephala, dry, pulverize, pass through a 80-100 mesh sieve, weigh 1 kg for later use;

[0087] (2) Add pure water with a volume equal to 20 times the mass of Atractylodes Rhizome powder to the above-mentioned Atractylodes Rhizoma Atractylodes Rhizome powder, decoct 3 times for 2 hours each time, take the juice and remove residue, combine the filtrates, and filter to obtain the aqueous extract solution of Atractylodes Rhizome;

[0088] (3) concentrating the Atractylodes Rhizome water extract solution under reduced pressure and low temperature to a specific gravity of 1.15;

[0089] (4) Slowly add 90% ethanol which is 8 times the volume of the above solution to the water extract solution of Atractylodes macrocephala concentrated under reduced pressure and lo...

Embodiment 2

[0091] Embodiment 2: the preparation of tablet

[0092] Take an appropriate amount of the effective part extracted in Example 1, concentrate it into an extract, spray dry it, process it into a fine powder, add commonly used pharmaceutical excipients according to the ratio of raw materials / excipients to about 7 / 3, and compress it into tablets using a common method Agent, sealed storage.

Embodiment 3

[0093] Embodiment 3: the preparation of oral liquid

[0094] Take an appropriate amount of the effective part extracted in Example 1, add an appropriate amount of pharmaceutically commonly used flavoring agent, and seal the package.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to an effective part of a traditional Chinese medicine, and particularly belongs to an effective part for treating spleen-deficiency type constipation by using rhizoma atractylodis. The effective part adopts a rhizoma atractylodis sugar compound as a main active component. The effective part can be prepared into various oral preparations including tablets, oral liquids, granules and capsules and the like by assistance of pharmaceutically-common auxiliary materials. Shown by pharmacological experiment results, the effective part has the advantages of action for treating the spleen-deficiency type constipation and obvious effect.

Description

technical field [0001] The invention relates to an effective part of a traditional Chinese medicine, in particular to an effective part of Atractylodes macrocephala for treating constipation of spleen deficiency type. [0002] technical background [0003] Constipation is a common clinical disease, which refers to the stagnation of feces in the intestinal cavity for too long, and the water is absorbed, resulting in constipation and difficulty in defecation. Constipation mainly includes two types: constipation caused by conduction dysfunction in the large intestine and constipation caused by spleen deficiency. Mild constipation has little impact on the human body, but severe constipation can seriously affect people's lives and bring great pain to people. It can cause abdominal pain and distension, blood in the stool, thrombotic hemorrhoids; induce or aggravate cardiovascular and cerebrovascular diseases in the elderly; Cause intestinal obstruction and life-threatening and so ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/715A61K36/284A61P1/10
Inventor 田薇蒋鹏王一李佳
Owner ZHEJIANG FORESTRY UNIVERSITY