Strong-stability 10% povidone-iodine solution for cows and preparation process thereof

Abstract

The invention belongs to the technical field of drug preparation and in particular relates to strong-stability 10% povidone-iodine solution for cows and a preparation process thereof. The solution is characterized by comprising the following components by weight percent: 10% of povidone-iodine, 1-5% of stabilizing agent, 1-10% of protective agent, 1-5% of antifreezing agent, 5-10% of surfactant, 5-20% of phosphate buffer and purified water. The preparation process comprises raw material treating, mixing, activating, filtering, PH value regulating, volume metering, subpackaging and sealing. Used before or after milking the cows, the solution prevents mastitis of the cows, simultaneously protects the nipples from frostbites and suncrack and ensures the stability during high and low temperatures.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparation, in particular to a 10% povidone-iodine solution with strong stability for dairy cows and a preparation process thereof. [0002] Background technique [0002] Povidone-iodine is recognized as a new type of high-efficiency, broad-spectrum, less irritating, no toxic and side effects, no residue, and no drug resistance. It has a strong killing effect on Staphylococcus aureus, Pseudomonas aeruginosa, hepatitis B virus, HIV, Trichomonas vaginalis, spores, etc., and can kill almost clinically common bacteria. But so far, povidone-iodine has a variety of iodine forms and is volatile. Under different pH values, the content of available iodine varies greatly, which affects its content and directly affects the therapeutic effect. The pH value of povidone-iodine solution is very unstable, and the drop is very large. At present, povidone-iodine is mostly newly formulated for immediate use, which...

AI Technical Summary

Problems solved by technology

3. Solve the problems of frostbite nipples and nipples that are easy to dry and crack when the temperature is too low

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