Formation method of drug coating and drug coating prepared by same
A technology of drug coating and drug molecules, applied in the field of medicine, can solve problems such as narrow space
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Embodiment 1
[0051] Example 1 Solid particle mixture according to one embodiment of the present invention
no. 1 approach
[0052] According to the first embodiment of the present invention, the drug coating formed by the mixture of solid particles can be formed by physical cross-linking of a single solid particle in a wet state. At this time, the "single solid particle" refers to a solid particle with the same form of expression. In this embodiment, the solid particle is a uniformly dispersed particle 2, such as figure 2 shown.
[0053] Usually, the solid particles at least include drug molecules and polymers, and the polymers can be a degradable hydrophilic / water-soluble polymer, or a combination of degradable polymers and hydrophilic / water-soluble polymers. mixture. Wherein, the drug molecules are uniformly dispersed in the polymer. For example in figure 2 and image 3 In , the number 21 indicates the degradable polymer, the number 22 indicates the hydrophilic / water-soluble polymer, and the number 23 indicates the drug molecule.
[0054] The method of forming the microparticles in uniform...
Embodiment 2
[0067] Example 2 Solid particle mixture according to another embodiment of the present invention
[0068] According to the second embodiment of the present invention, the drug coating formed by the mixture of solid particles can be formed by physical cross-linking of a single solid particle in a wet state. At this time, the "single solid particle" refers to a solid particle with the same form of expression. In this embodiment, the solid particle is a particle 3 in the form of a skin-core, such as Figure 7 shown.
[0069] Usually, the solid particles at least include drug molecules and polymers, and the polymers can be a degradable hydrophilic / water-soluble polymer, or a combination of degradable polymers and hydrophilic / water-soluble polymers. mixture. Wherein, the drug molecules are uniformly dispersed in the polymer. For example in Figure 7 In , the number 31 represents a degradable polymer, the number 32 represents a hydrophilic / water-soluble polymer, and the number...
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