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Method for preparing medicament for treating leucopenia

A technology for leukopenia and medicament, applied in the field of medicine, can solve the problems of large side effects, poor curative effect, high price, etc.

Inactive Publication Date: 2013-04-24
朱家红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine often uses drugs such as batalinol, lexogen, and Ruibai for treatment, but the curative effect is poor and the side effects are relatively large
Although the granulocyte colony factor used in recent years has a certain curative effect, it is expensive and has many side effects, which limits the promotion of the drug

Method used

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  • Method for preparing medicament for treating leucopenia
  • Method for preparing medicament for treating leucopenia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] Raw materials: 5 parts of American ginseng, 3 parts of astragalus, 2 parts of Panax notoginseng, 3 parts of Ganoderma lucidum, 3 parts of Ligustrum lucidum, 6 parts of Caulis Spatholobus, 3 parts of medlar, 3 parts of white peony root, 3 parts of psoraleae, donkey-hide gelatin 2 parts, 3 parts tangerine peel;

[0065] (1) Take the above-mentioned medicinal materials in proportion, add 6 times the amount of 60% ethanol of the medicinal materials, carry out reflux extraction twice, each time for 1 hour, combine the ethanol extract, recover the ethanol until it has no alcohol smell, and obtain the extract;

[0066] (2) Take the dregs extracted by ethanol, add 4 times the amount of water to decoct twice, 1 hour each time, combine the decoction, and concentrate (the relative density is 1.10 when measured at 60°C);

[0067] (3) Combine the ointments obtained in (1) and (2), and concentrate under reduced pressure to form a thick ointment (relative density measured at 60°C is 1...

Embodiment 2

[0070] Raw materials: 8 parts of American ginseng, 5 parts of Astragalus, 5 parts of Panax notoginseng, 8 parts of Ganoderma lucidum, 8 parts of Ligustrum lucidum, 10 parts of Caulis Spatholobus, 8 parts of medlar, 8 parts of white peony root, 8 parts of psoraleae, donkey-hide gelatin 5 parts, 8 parts tangerine peel;

[0071] (1) Take the above-mentioned medicinal materials in proportion, add 10 times the amount of 80% ethanol of the medicinal materials to carry out reflux extraction for 4 times, each time for 3 hours, combine the ethanol extract, recover the ethanol until it has no alcohol smell, and obtain the extract;

[0072] (2) Take the dregs extracted by ethanol, add 6 times the amount of water to decoct 4 times, 3 hours each time, combine the decoction, and concentrate (the relative density is 1.10 when measured at 60°C);

[0073] (3) Combine the ointments obtained in (1) and (2), and concentrate under reduced pressure to form a thick ointment (relative density measure...

Embodiment 3

[0076] Raw materials: 6 parts of American ginseng, 4 parts of Astragalus, 3 parts of Panax notoginseng, 6 parts of Ganoderma lucidum, 6 parts of Ligustrum lucidum, 8 parts of Caulis Spatholobus, 6 parts of medlar, 5 parts of white peony root, 5 parts of psoraleae, donkey-hide gelatin 4 parts, 6 parts of tangerine peel;

[0077] (1) Take the above-mentioned medicinal materials in proportion, add 8 times the amount of 70% ethanol of the medicinal materials to carry out reflux extraction for 3 times, each time for 2 hours, combine the ethanol extract, recover the ethanol until it has no alcohol smell, and obtain the extract;

[0078] (2) Take the dregs extracted by ethanol, add 5 times the amount of water to decoct 3 times, 2 hours each time, combine the decoction, and concentrate (the relative density is 1.10 when measured at 60°C);

[0079] (3) Combine the ointments obtained in (1) and (2), and concentrate under reduced pressure to form a thick ointment (relative density measur...

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Abstract

The invention relates to a method for preparing a medicament for treating leucopenia. The preparation method comprises the following steps of: taking medicinal materials in a ratio, adding 60 to 80 percent ethanol in an amount which is 6 to 10 times the weight of the medicinal materials, performing reflux extraction for 2 to 4 times and 1 to 3 hours every time, combining the ethanol extracts, and recovering the ethanol till the ethanol smell does not exist to obtain paste; decocting the medicinal residue for 2 to 4 hours and 1 to 3 hours every time by adding water in an amount which is 4 to 6 times the weight of the medicinal residue, combining the decoction, and concentrating; and combining the medicinal paste, concentrating the medicinal paste into thick paste under reduced pressure, adding available medicinal accessories into the thick paste, thus obtaining a clinical available preparation. The medicament has the effects of nourishing liver and kidney and tonifying qi and blood, and is clinically used for treating the leucopenia produced after malignant tumor radiotherapy and chemotherapy.

Description

technical field [0001] The invention relates to a preparation method of a medicament for treating leukopenia, more specifically, a preparation method of a medicament that has the functions of nourishing the liver and kidney and benefiting qi and blood; it is clinically used to treat leukopenia caused by malignant tumor radiotherapy and chemotherapy. The preparation method belongs to the technical field of medicine. Background technique [0002] Leukopenia is a common blood disease and belongs to the category of asthenia and blood deficiency in traditional Chinese medicine. Doctor trained in Western medicine uses the medicine treatment such as batyl alcohol, lexogen, Ruibai more, but curative effect is relatively poor, and side effect is bigger. Although the granulocyte colony factor used in recent years has a certain curative effect, it is expensive and has many side effects, which limit the promotion of the drug. [0003] The TCM syndrome differentiation of leukopenia bel...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61P7/00A61K35/36
Inventor 朱家红
Owner 朱家红
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