High-penetrating agent and preparation method thereof

A high penetration and active agent technology, applied in the direction of detecting the appearance of fluid at the leakage point, using liquid/vacuum degree for liquid tightness measurement, etc., can solve problems such as rework, quality hidden dangers, and failure to detect, and achieve detection time The effect of shortening, reducing quality hidden dangers, and reducing testing costs

Active Publication Date: 2013-08-21
SHIJIAZHUANG NO 4 PHARMA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] When the above-mentioned prior art detects the tightness of plastic infusion containers, micropores are difficult to detect or cannot be detected, and the time required for detection is long, which affects the inspection cycle and quality control of products.
When detecting the welding micropores of PP packaging materials, the external force must overcome the surface tension of the liquid on the micropores under pressurized state. Usually, it takes 2 days to find the micropores, but even so, there are still undetectable Case
Moreover, this detection method can only be used for the detection of finished products. It must be a finished product that has been filled and after sterilization and disinfection, it can only be detected under the condition of applying external force.
This detection method lags behind the actual production. After the detection results come out, a large number of finished products have been produced. If there are micropores, all finished products must be reworked, which wastes a lot of manpower and material resources, and there is a great quality hidden danger.

Method used

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Embodiment Construction

[0015] The high penetration agent of the present invention is composed of surfactant, organic solvent, pigment and water according to a certain ratio. It improves the surface wettability of water and plastic transfusion containers through the double functions of the hydrophilic group and the lipophilic group of the surfactant, and plays an excellent penetrating effect. In the high penetration agent, the content of the surfactant will play a key role in the detection time, and the detection time will be shortened as the proportion of the surfactant increases. In practical application, as the batch inspection of the laboratory, that is, the release inspection of the laboratory inspector, the general detection cut mark is kept for 30 minutes, and the welding and sealing inspection is left for two hours to determine whether the batch of products meets the airtightness requirements, so that Release the batch of products; rapid inspection during the production process, that is, the ...

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Abstract

The invention discloses a high-penetrating agent and a preparation method of the high-penetrating agent. The high-penetrating agent comprises, by weight, 0.05%-1.0% of surfactant, 2%-8% of organic solvent, 0.05%-1.0% of pigment, and the balance water. The surfactant is anionic surfactant or nonionic surfactant. The invention further provides the preparation method of the high-penetrating agent. Experiments show that the high-penetrating agent is good in detection effect of tightness of pull ring cutting mark and welding of a plastic infusion container, and capable of shortening the detection time. Particularly, the welding tightness of semi-finished products can be directly detected, the detection period can be controlled to be within two hours. The above advantages bring great convenience to adjustment of equipment and the technology on production site, reduce detection cost, and greatly reduce potential quality hazard caused by detection errors of the products.

Description

technical field [0001] The invention relates to a penetrant and a preparation method, in particular to a high penetrant for testing the tightness of plastic transfusion containers and a preparation method. Background technique [0002] At present, plastic infusion containers are commonly used in clinical infusion, which are composed of plastic infusion bags and polypropylene combined caps (ring-pull type) through welding. The main component of the infusion solution is water. Under the effect of surface tension, the surface wettability between the solution and the plastic infusion container for infusion is poor. In the case of micropores in the plastic infusion container for infusion, the solution is not easy to seep out under the action of external force. , and after about 7 days of storage, the liquid medicine will seep out in a small amount, and there is a great quality hidden danger. At present, the only penetrant used to check the tightness of plastic infusion container...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01M3/20G01M3/04
Inventor 曲继广韩淑芹王春发蒋德光宋立军李俊德韩同乐关珊马辉张红莲
Owner SHIJIAZHUANG NO 4 PHARMA
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