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Extract from traditional Chinese medicine and its preparation method

A technology of extracts and natural medicines, applied in drug combinations, pharmaceutical formulas, anti-tumor drugs, etc., can solve the problems of patients with dehydration, acid-base balance imbalance, malnutrition, etc., to achieve increased inhibition, enhanced inhibition, and good synergy The effect of action

Inactive Publication Date: 2013-08-28
阚兆云
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AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, etc., the incidence of chemotherapy-related diarrhea has increased year by year, and if active treatment is not carried out, it is easy to cause Dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc. in patients not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Therefore, effective treatment of chemotherapy-related diarrhea has become a An important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Extract from traditional Chinese medicine and its preparation method
  • Extract from traditional Chinese medicine and its preparation method

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Experimental program
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Embodiment approach

[0034] The first step: preparation of various extracts

[0035] (1) Preparation of Coptidis Scutellariae Scutellariae Decoction Concentrated Extract

[0036] According to the compatibility ratio of 1:1 or 1-4:1, take Coptis chinensis and Scutellaria baicalensis, soak in 10 times the amount of distilled water for 1 hour, heat and decoct on an electric stove with asbestos net for 1 hour, filter with silk cloth, save the filtrate, add the dregs 6 times of distilled water, soaking, decocting, and filtering in the same way, mixing the two filtrates, heating and concentrating to a small volume, filtering with an ultrafiltration membrane, and drying under reduced pressure at 70°C for 36 hours in a vacuum drying oven to obtain a brownish-yellow powder.

[0037] (2) preparation of berberine

[0038] Coptis rhizome is crushed, add ethanol, heat and reflux in water bath for 0.5h, suction filter, repeat the above operation twice for the filter residue, combine the filtrate, recover ethan...

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Abstract

The invention relates to a natural pharmaceutical composition, preparation method thereof and the usage in preparing an attenuated synergistic medicament in cancer chemotherapy, wherein the natural pharmaceutical composition consists of rhizoma coptidis and Scullcap decoction condensation extract product, berberine, scullcap general flavone and scutelloside in a proportion of 2-4:3-7:3-6:4-8. The composition has good curative effect to cancer chemotherapy related diarrhoea and cancer chemotherapy.

Description

technical field [0001] The present invention relates to a natural medicinal composition, more specifically to a natural medicinal composition composed of Coptidis Radix Scutellariae decoction concentrated extract, berberine, total flavonoids of Scutellaria baicalensis and baicalin, the preparation method of the natural medicinal composition and Use of the natural medicine composition for preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called chemotherapy-associ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61P35/00A61P1/12A61K31/4375A61K31/7048
Inventor 阚兆云
Owner 阚兆云
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