Antibacterial medical suture and preparation method thereof

Abstract

The invention discloses an antibacterial medical suture and a production method thereof. A titanium-nickel memory alloy thread is adopted as a base material of the antibacterial medical suture. A silver-ion cladding layer with thickness of 0.1-1 micrometer is deposited on the surface of the base material. The production method includes depositing the silver-ion cladding layer on the base material in winding-type continuous coating equipment by a physical vapor deposition method. The antibacterial medical suture has functions of sterilization and bacteriostasis, and silver ions contact with positions of cuts, wounds and needle holes, so that infection prevention and resistance are realized; the antibacterial medical suture further keeps all properties of existing titanium-nickel memory alloy while having an antimicrobial property, is stable in chemical property, and can meet the requirements on stitching of infected wounds and seborrheic cuts; rejection is avoided during long-term in-vivo implantation, mechanical property is not changed, and the purposes of freeness of trauma, hyperplasia and in-vivo foreign matters are achieved.

Description

technical field [0001] The invention relates to an antibacterial medical suture and a preparation method thereof. Background technique [0002] Ordinary silk suture skin often leaves obvious stitches or even scars on both sides of the incision margin, which not only affects the appearance, but sometimes is accompanied by itching, acupuncture-like pain and other discomforts. To this end, people have carried out various explorations on suturing skin materials. [0003] At present, the hospital clinically uses a medical suture thread made of titanium-nickel memory alloy wire, and one or both ends of the suture thread are connected with suture needles of different specifications and shapes made of stainless steel, such as triangular needles, curved round needles, Straight circular needles, spade needles, etc., use the shape memory function of titanium-nickel memory alloy and the superelasticity after phase transition, suture with intradermal suture method, make the wound butt a...

AI Technical Summary

Problems solved by technology

[0004] Although silver ions have broad-spectrum antibacterial properties, their coating processing is difficult, because the first prerequisite for coating the surface of titanium-nickel memory alloy sutures is to ensure that the shape memory of the sutures is maintained after coating, and the thread body conforms to medical metal sutures. Otherwise, once it loses its memory function or other physical properties change, it will lose the meaning of clinical suture use

Therefore, when using any coating process, it should be considered whether it will affect the change of the physical properties of the substrate. If the electroplating method is used to coat the surface of the titanium-nickel memory alloy suture, there will be pollution such as cyanide and residual substances harmful to the human body.

In addition, the temperature is generally 70-90°C or even higher, and the film layer is too thick, which affects the mechanical structure of the titanium-nickel memory alloy wire, resulting in changes in mechanical elasticity and temperature sensing of the body, which will cause changes in the atomic sequence inside the wire. Lose shape memory performance or deformation; using liquid chemical deposition (LPD), the silver salt produced has certain toxicity and has a staining effect on skin tissue; chemical vapor deposition (CVD), the deposited layer is usually a columnar crystal structure , not resistant to bending, easy to break; using nano-silver coating, the adhesion between the substrate and the coating is low, easy to fall off, easy to enter the human blood microcirculation system and cause unpredictable damage, and cause local argyria and eye problems , the risk of respiratory damage, etc.

[0005] At present, using titanium-nickel memory alloy wire as the substrate, a layer of silver ion plating is deposited on the surface of the substrate to obtain a new medical suture has not been reported.