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Method of extracting active molecules from natural resins and use thereof

A technology of active molecules, extracts, applied in the field of preparation of food compositions or supplements or pharmaceutical compositions

Inactive Publication Date: 2013-10-09
RODE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Another limitation given is that it must operate in magnetic fields containing 1000 to 3500 Gauss

Method used

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  • Method of extracting active molecules from natural resins and use thereof
  • Method of extracting active molecules from natural resins and use thereof
  • Method of extracting active molecules from natural resins and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0146] Example 1 - Myrrh

[0147] The extraction method of the present invention is used to extract active molecules contained in myrrh. The extraction apparatus was loaded with 1500 ml of extraction solvent comprising: acetic acid (12% in water), 58% by weight, and distilled water, 42% by weight. The solvent:myrrh ratio was 15:1 by weight; 100 g of myrrh was finely ground (particle size inclusive 100-120 microns). Carbon dioxide was used in an amount of 30 ml (2% by volume, relative to the total volume of the extraction solvent). A predetermined amount of extraction solvent (1500 ml) was introduced into tank 01 and kept under stirring at 50 rpm using stirring device 02 for 15 minutes. The extraction solvent flows from tank 01 to tank 05 using pump 03 and connection 04 . Tank 05 is equipped with heating means 06 and stirring means 09 . 100 g of myrrh were weighed and ground (particle size comprised 40-100 microns), introduced into tank 11 and kept under stirring using stir...

Embodiment 2

[0148] Example 2 - Agarwood

[0149] The extraction method of the present invention is used to extract active molecules contained in agarwood. Example 2 was carried out with the same procedure as described in Example 1, with the only differences as described below. The extraction apparatus was loaded with 1500 ml of extraction solvent comprising: acetic acid (12% in water), 58% by weight; 99% ethanol, 20% by weight, and distilled water, 22% by weight. The solvent: agarwood ratio was 15:1 by weight; 100 g of agarwood was finely ground (particle size inclusive 100-120 microns). Carbon dioxide was used in an amount equal to 30 ml (2% by volume, relative to the total volume of the extraction solvent). As can be seen from Table 2, 46 active molecules were extracted from Agarwood. The extraction yield by weight was 125,000 ppm, corresponding to 12.5% ​​of 100 g of agarwood, relative to the total weight of extractable substances initially present in 100 g of agarwood.

Embodiment 3

[0150] Example 3 - Brachyphyllum

[0151]The extraction method of the present invention was used to extract active molecules contained in Pittonia brevis (abbreviated as TP). Example 3 was carried out with the same operating steps as described in Example 1, with the only differences as described below. The extraction apparatus was loaded with 1500 ml of extraction solvent comprising: acetic acid (12% in water), 40% by weight, and distilled water, 60% by weight. Solvent:TP ratio was 15:1 by weight; 100 g of TP was finely ground (particle size inclusive 100-120 microns). Carbon dioxide was used in an amount equal to 45 ml (3% by volume, relative to the total volume of the extraction solvent). As can be seen from Table 3, 49 active molecules were extracted from Agarwood. The extraction yield by weight was 85,000 ppm, corresponding to 8.5% of 100 g of TP, relative to the total weight of extractable material initially present in 100 g of TP.

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Abstract

The present invention relates to a method of extracting active molecules from natural resins and / or essential oils. In particular, the present invention relates to a method of extracting active molecules selected from the group comprising terpenes, flavonoids, anthocyanins and catechins. Moreover, the present invention relates to an extract, preferably in liquid form, obtained with said method. Finally, the present invention relates to the use of said extract containing the active molecules selected from the group comprising terpenes, flavonoids, anthocyanins and catechins for the preparation of a food composition or supplement or a pharmaceutical composition.

Description

technical field [0001] The present invention relates to methods for extracting active molecules from plant matrices, natural resins and / or essential oils. In particular, the present invention relates to a method for the extraction of active molecules selected from the group comprising terpenes, flavonoids, anthocyanins and catechins. Furthermore, the invention relates to the extract, preferably in liquid form, obtained by said method. Finally, the invention relates to the use of said extract comprising active molecules selected from the group comprising terpenes, flavonoids, anthocyanins and catechins for the preparation of food compositions or supplements or pharmaceutical compositions. Background technique [0002] Natural resins such as myrrh, incense and propolis are known to contain a large number of active molecules such as terpenes and / or flavonoids and the like. One can find for example monoterpenes (2 isoprene units and 10 carbon atoms), sesquiterpenes (3 isoprene...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01D11/02A61K36/00A23L1/30A61K8/97A61K8/98A61K31/353A61K36/328
CPCB01D11/0284A61K35/644B01D11/0257A61K2236/30A61K36/28A61K36/328A23L1/2215A61K36/45A23L1/3002A23L27/11A23L33/105A61K36/00A61K8/98A61K8/97A61K2121/00B01D11/02
Inventor 路易吉·阿梅罗蒂洛伦佐·赛肯迪尼
Owner RODE PHARMA
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