A pharmaceutical composition for enhancing the memory of people rapidly advancing to plateau and its preparation method

A composition and memory technology, applied in the field of medicine, can solve the problems of insignificant improvement of memory loss and the like, and achieve the effects of enhancing memory and improving memory

Active Publication Date: 2016-01-13
URUMQI GENERAL HOSPITAL LANZHOU MILITARY AREA CHINESE P L A
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned anti-altitude hypoxia drugs have no significant effect on improving memory loss caused by acute hypobaric hypoxia.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] A pharmaceutical composition for enhancing the memory of people rapidly advancing to high altitudes, including active ingredients taurine, egg yolk lecithin, acetyl-L-carnitine and huperzine A totaling 300 mg; excipients lactose 124 mg, MCC 46 mg, magnesium stearate 8 mg, the active ingredients The ingredients, lactose, and MCC are mixed evenly, moistened with water, the wetted mixture is sieved and dried, sieved, magnesium stearate is added, mixed evenly, and tabletted.

[0019] Active ingredients per unit dosage form: 128mg taurine; 128mg egg yolk lecithin; 44mg acetyl-L-carnitine; 0.8mg huperzine A.

[0020] Prove the beneficial effect of medicine of the present invention below by pharmacodynamics test:

[0021] (1) Materials and methods

[0022] 1. Drugs:

[0023] The prepared pharmaceutical composition of embodiment 1;

[0024] Salidroside, purity >90% (HPLC).

[0025] 2. Screening and grouping of experimental animals:

[0026] Healthy male Sprague-Daw...

Embodiment 2

[0095] A pharmaceutical composition for enhancing the memory of people rapidly advancing to high altitudes, including active ingredients taurine, egg yolk lecithin, acetyl-L-carnitine and huperzine A in total 300 mg; excipients lactose 87 mg, magnesium stearate 5 mg, the active ingredients, The lactose is mixed evenly, moistened with water, the wetted mixture is sieved and dried, sieved, magnesium stearate is added, mixed evenly, and packed into capsules.

[0096] Active ingredients per unit dosage form: 128mg taurine; 128mg egg yolk lecithin; 44mg acetyl-L-carnitine; 0.8mg huperzine A.

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PUM

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Abstract

The invention discloses a pharmaceutical composition for enhancing the memory of people rapidly entering plateaus. The pharmaceutical composition is composed of active components and auxiliary materials; the active components are composed of taurine, egg yolk lecithin, acetyl-L-carnitine and huperzine A Composition; The excipients consist of lactose, MCC and magnesium stearate or consist of lactose and magnesium stearate. The beneficial effects of the present invention are as follows: the pharmaceutical composition provided by the present invention for enhancing the memory of people rapidly advancing to plateau provides essential nutrients for nerve cells, scavenging free radicals, supplementing neurotransmitter acetylcholine precursors, and regulating the functions of the central cholinergic system, etc. Starting from different mechanisms of action, they act comprehensively on the body, which embodies the advantages of combined medication and achieves the effect of improving the memory of people who are rapidly entering the plateau.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a pharmaceutical composition for enhancing the memory of people rapidly advancing to plateaus and a preparation method thereof. Background technique [0002] After entering the plateau, people living in the plains often cause a series of acute altitude sickness due to low air pressure and hypoxia, including dizziness, palpitation, nausea, insomnia, memory loss and other symptoms. The above symptoms are more obvious. [0003] Both animal model experiments and clinical imaging studies of people rapidly entering high altitudes have shown that acute hypobaric hypoxia can lead to damage to brain hippocampal neurons. On the basis of such pathological changes, people who rapidly enter the plateau may experience cognitive dysfunction, including learning disabilities, memory difficulties, and attention deficits. Eventually lead to a significant decline in the level of vocational skills. [000...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/685A61P25/28A61P39/06A61K31/4748A61K31/221A61K31/185
Inventor 史清海张琼赵红艳伏建峰葛迪冉继华刘正祥袁文常王黎
Owner URUMQI GENERAL HOSPITAL LANZHOU MILITARY AREA CHINESE P L A
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