Method for synthesis of calcium alginic acid monosaccharide from shells and alginic acid

Abstract

The invention relates to a method for synthesis of calcium alginic acid monosaccharide from shells and alginic acid. The method comprises shell pre-treatment, alginic acid degradation, synthesis, crystallization, and drying. The method comprises the following steps of 1, immersing shells in hydrochloric acid having the content of 0.05M, carrying out drying, carrying out crushing, carrying out treatment by an elutriation method to obtain calcium-source shell powder, adding alginic acid into an appropriate amount of a H2O2 solution having the content of 3%, carrying out heating degradation by a water-bath heating and microwave heating combined method, wherein in the heating degradation, a water-bath heating process is carried out at a temperature of 80 DEG C for 1h, then a microwave heating process is carried out for 1.5h, then a water-bath heating process is carried out at a temperature of 80 DEG C for 1h and then a microwave heating process is carried out for 1h, and carrying out centrifugation, purification, concentration and drying of the degradation products to obtain white alginic acid monosaccharide, and 2, dissolving the white alginic acid monosaccharide in an appropriate amount of distilled water, adding the calcium-source shell powder into the alginic acid monosaccharide solution according to a mole ratio of the alginic acid monosaccharide to the shell powder of 2: 1.0-1.2, wherein the calcium carbonate content is 95%, carrying out a reaction in a water bath at a temperature of 30 DEG C for 0.75h, carrying out suction filtration, and carrying out reduced pressure concentration, alcohol precipitation crystallization and drying of the supernatant. The method has simple processes. The calcium alginic acid monosaccharide can be used as a novel calcium supplement agent. The method realizes high-value utilization of alginic acid and a plurality of shells.

Description

technical field [0001] The invention relates to a method for synthesizing alginic acid monosaccharide calcium by using shellfish processing waste and alginic acid as raw materials through high-value and clean process steps to realize high-efficiency utilization of shellfish processing waste and alginic acid. Background technique [0002] Calcium is one of the indispensable nutrients for the human body. It plays an important role in bone formation, muscle contraction, heart beating and brain thinking activities, eliminating fatigue, strengthening the brain and delaying aging. At present, most calcium supplements that have been widely used are calcium carbonate, calcium gluconate, calcium lactate, etc. my country is rich in aquatic product resources, but a large amount of waste (oyster shells, scallop shells and clam shells, etc.) produced by shellfish processing has yet to be developed and applied. [0003] The complete degradation products of alginic acid are D-mannuronic a...

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Problems solved by technology

[0003] The complete degradation products of alginic acid are D-mannuronic acid and L-guluronic acid, both of which have unique physiological activities: D-mannuronic acid has the functions of anticoagulation, reducing blood viscosity, improving microcirculation, etc. And L-guluronic acid also has the effect of improving blood microcirculation. At present, there are very few studies on the degradation of monosaccharides by alginic acid at home and abroad.