Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Famciclovir tablet and preparation method thereof

A technology of famciclovir tablet and famciclovir is applied in the field of famciclovir tablet and its preparation, which can solve the problems of affecting drug efficacy, famciclovir dissolution rate and providing corresponding technical solutions.

Inactive Publication Date: 2013-12-25
ZIBO DINGLI PATENT INFORMATION CONSULTING CO LTD
View PDF4 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] It is found through retrieval that none of the prior art provides corresponding technical solutions on how to improve the dissolution rate of famciclovir, and the inventor considers that the dissolution of the drug affects the drug effect, so he intends to develop a fast-dissolution famciclovir tablet

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Famciclovir tablet and preparation method thereof
  • Famciclovir tablet and preparation method thereof
  • Famciclovir tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1 famciclovir tablet and preparation method thereof

[0022]

[0023] Preparation:

[0024] The prescription quantity takes famciclovir and sodium bicarbonate, adds them into pure water, stirs to dissolve, and uses this aqueous solution as a wetting agent, joins on the microcrystalline cellulose that the prescription quantity passes through a 100-mesh sieve, granulates, and dries at 60°C. Sieve with 18 meshes for granulation, mix the dry granules with magnesium stearate evenly, and press into tablets.

Embodiment 2

[0025] Embodiment 2 famciclovir tablet and preparation method thereof

[0026]

[0027] Preparation:

[0028] Weigh the famciclovir and sodium bicarbonate in the prescription quantity, add them into pure water, stir to dissolve, use this aqueous solution as a wetting agent, add it to the lactose that has passed the 100-mesh sieve in the prescription quantity, granulate, dry at 50°C, and use a 20-mesh sieve Whole granules, dry granules mixed with magnesium stearate, compressed into tablets.

Embodiment 3

[0029] Embodiment 3 famciclovir tablet and preparation method thereof

[0030]

[0031]

[0032] Preparation:

[0033] The prescription quantity takes famciclovir and sodium bicarbonate, adds them into pure water, stirs to dissolve, and uses this aqueous solution as a wetting agent, joins on the microcrystalline cellulose that the prescription quantity passes through a 100-mesh sieve, granulates, and dries at 55°C. Sieve with 18 meshes for granulation, mix the dry granules with magnesium stearate evenly, and press into tablets.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an antivirus famciclovir tablet. According to the tablet, an aqueous solution of famciclovir and sodium bicarbonate serves as a wetting agent. The tablet is prepared through the wet granulating and tabletting of the following ingredients in parts by weight: 100 parts of famciclovir, 40-65 parts of sodium bicarbonate, 80-200 parts of bulking agent and an appropriate amount of lubricant. Compared with the prior art, the tablet and the preparation method thereof have the advantages that the tablet can be rapidly disintegrated and dissolved without adding a disintegrant, and meanwhile, the preparation method is simple and is suitable for the requirements for large-scale production.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical preparations, and in particular relates to an antiviral famciclovir tablet and a preparation method thereof. Background technique [0002] Famciclovir is the diethyl acyl ester of the 6-deoxy derivative of penciclovir, the molecular formula is C14H19N5O4, and the chemical name is 2-[2-(2-amino-9H-purin-9-yl) Ethyl]-1,3-propanediol-diethyl ester, suitable for the treatment of herpes zoster and primary genital herpes, has become one of the main drugs sold worldwide. The structural formula is: [0003] [0004] CN101904825A discloses a famciclovir dispersible tablet and a preparation method thereof. This technology only prepares a kind of dispersible tablet, but shortens the disintegration time, and the dissolution of the tablet that disintegrates rapidly is not necessarily fast. [0005] It is found through retrieval that none of the prior art provides a corresponding technical solution...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K9/46A61K31/52A61K33/00A61P31/22
Inventor 不公告发明人
Owner ZIBO DINGLI PATENT INFORMATION CONSULTING CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com