Traditional Chinese medicine composition for treating vaginitis and preparation method thereof

A composition and vaginitis technology, applied in the direction of drug combination, pharmaceutical formula, hydroxyl compound active ingredients, etc., can solve the problems of vaginal flora imbalance, candida infection, etc.

Active Publication Date: 2016-04-27
黄德明
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the abuse of antibiotics can lead to vaginal flora imbalance, the longer the antibiotics are used, the more chances of candida infection

Method used

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  • Traditional Chinese medicine composition for treating vaginitis and preparation method thereof
  • Traditional Chinese medicine composition for treating vaginitis and preparation method thereof
  • Traditional Chinese medicine composition for treating vaginitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] Embodiment 1: scheme one lotion

[0091] Take 35g of Cortex Phellodendron, 35g of Baibu, and 15g of Fructus Cnidii into coarse powder, add 1% acetic acid and 10% ethanol solution and soak for 48 hours. The 10% ethanol solution of acetic acid is infiltrated at a rate of 20ml per kilogram of medicinal material per minute, and the percolation liquid that is 6 times the weight of the medicinal material is collected. Take 3g of the total alkaloids of Sophora sophora, add acetic acid and water to dissolve, and add 0.2g of menthol to the percolation solution. liquid, mix evenly, finally add water to 10 times of the crude drug amount of feeding, add the benzoic acid of 0.15% of the total weight of the liquid medicine, stir evenly, filter, obtain the lotion of the present invention.

Embodiment 2

[0092] Embodiment 2: scheme one ointment

[0093] Take 30g of Cortex Phellodendri, 30g of Baibu, and 12g of Fructus Cnidii into coarse powder, add 1% acetic acid and 5% ethanol solution and soak for 24 hours. The 5% ethanol solution of acetic acid is infiltrated at a rate of 30ml per kilogram of medicinal material per minute, and the percolation liquid that is 8 times the weight of the medicinal material is collected. Take 2g of the total alkaloids of Sophora sophora, add acetic acid and water to dissolve, and add 0.2g of menthol to the percolation solution. Liquid, mix, obtain active ingredient of the present invention; Get salicylic acid 4g, stearic acid 10g, glyceryl monostearate 5.6g, white petrolatum 0.8g, lanolin 4g, liquid paraffin 4.8g, Tween 800.32g, Add distilled water to 80g, make emulsifier matrix by conventional method, add above-mentioned active ingredient of the present invention, make ointment.

Embodiment 3

[0094] Embodiment 3: scheme one suppository

[0095] Take 40g of Cortex Phellodendri, 40g of Baibu and 20g of Fructus Cnidii into coarse powder, add 2% acetic acid and 30% ethanol solution and soak for 60 hours. The 30% ethanol solution of acetic acid is infiltrated at a rate of 10ml per kilogram of medicinal materials per minute, and the percolation liquid that is 4 times the weight of the medicinal materials is collected. Take 4g of the total alkaloids of Sophora sophora, add acetic acid and water to dissolve, and add 0.4g of menthol to the percolation solution. liquid, and mix evenly to obtain the active ingredient of the present invention; take the semi-synthetic fatty acid ester twice the weight of the active ingredient, heat and melt it in a water bath, take the fine powder of the active ingredient after grinding, add it to the molten matrix in stages, and stir evenly. Pour into the mold of lubricant, demold after cooling and solidification, obtain suppository of the prese...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating vaginitis and a preparation method thereof. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: total alkaloids of Sophora sophorae, Phellodendron officinalis officinalis, Rhizoma chinensis, Fructus Cnidii and Menthol. It is suitable for symptoms such as vulvar itching and pain caused by damp-heat vaginitis syndrome. In addition, the invention also provides an extraction method of a traditional Chinese medicine composition containing Cortex Cortex Phellodendri, Rhizoma Cortex Bulb and Fructus Cnidii. The traditional Chinese medicine composition provided by the invention has definite curative effect in treating damp-heat type vaginitis, and the effect is better than that of the prior art. The extraction method of the traditional Chinese medicine composition provided by the invention can increase the content of active ingredients, and is beneficial to the stability of the final solution dosage form product, so that the product can obtain better appearance and quality.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating vaginitis and a preparation method thereof. Background technique [0002] Vaginitis can occur at any time in a woman's life. Vaginitis is an inflammatory response caused by pathogenic microorganisms (including fungi, bacteria, trichomonas and other microorganisms) infection. Vaginitis can be divided into fungal vaginosis (also known as candida vaginosis), senile vaginitis, trichomonal vaginitis, bacterial vaginosis and so on. Various types of vaginitis have the symptoms of increased leucorrhea, frequent urination, urgency, and painful urination. There are varying degrees of itching, burning or pain in the vulva, and the acute stage will be accompanied by fever. Although the symptoms are similar, the medications for different types of vaginitis (disease) are very different. [0003] The highest incidence rate is...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/904A61P15/02A61P17/04A61P31/02A61P31/04A61P31/10A61P33/02A61K31/045
Inventor 黄德明
Owner 黄德明
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