Device for detecting tumor characters by Raman spectrum

A Raman spectroscopy detection and Raman spectroscopy technology, applied in Raman scattering, material excitation analysis, etc., can solve the problems of difficult clinical portable applications, bulky instruments, and easily damaged samples, achieve fast and non-invasive measurement, reduce calculation The effect of volume and rapid collection

Active Publication Date: 2014-03-19
BEIHANG UNIV
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  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

Some of these technologies have the problems of bulky and expensive instruments, and some require sample processing, which is easy to damage the sample, and it is not easy to realize portable clinical application.

Method used

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  • Device for detecting tumor characters by Raman spectrum
  • Device for detecting tumor characters by Raman spectrum
  • Device for detecting tumor characters by Raman spectrum

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Embodiment Construction

[0040] The device of the present invention will be further described below in conjunction with the accompanying drawings and specific embodiments, so that those skilled in the art can better understand the present invention and implement it, but the embodiment of the detection of the properties of breast tumors is not regarded as the embodiment of the present invention limited.

[0041] figure 1 A block diagram of the overall composition of the device for detecting tumor properties using Raman spectroscopy provided by the present invention; figure 2 It is a schematic diagram of the overall connection of the device for detecting tumor properties by using Raman spectroscopy provided by the present invention. Such as figure 1 , figure 2 As shown, the device for detecting tumor properties using Raman spectroscopy mainly includes the following modules:

[0042] Spectrometer module 1 : mainly includes a laser light source 101 and a Raman spectrometer 102 . The laser light sou...

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Abstract

The invention discloses a device for detecting tumor character by Raman spectrum. The device comprises a spectrometer module, a sampling module and a control and data processing module, wherein the spectrometer module comprises a laser light source and a Raman spectrometer; the laser light source is used for providing the laser needed by detection; the Raman spectrometer is used for acquiring the Raman spectrum of a sample to obtain a digital signal containing sample molecular information; the sampling module comprises optical fibers and an optical fiber probe; the optical fiber probe is used for collecting the Raman spectrum; the laser light source is connected with the optical fiber probe by the optical fiber, and the optical fiber probe is connected with the Raman spectrometer by the optical fiber; the control and data processing module comprises an embedded microprocessor which is respectively connected with the laser light source and the Raman spectrometer, so that the Raman spectrometer and the laser light source can be controlled in the detection process; and the control and data processing module can be used for judging the tumor character by processing the spectral data after reading the digital signal acquired by the Raman spectrometer. The portable device supports in vivo or in vitro test and is capable of carrying out rapid clinical diagnosis on the tumor character.

Description

technical field [0001] The invention relates to medical detection equipment, in particular to a device for detecting tumor properties by using Raman spectrum. Background technique [0002] Malignant tumors have become one of the major diseases that seriously endanger human health and life in the world, occupying the first place in the mortality rate of urban residents in my country, and seriously threatening human health. For malignant tumors, early detection, early diagnosis, and early treatment are the key to improving the quality of life and prolonging the survival time of patients. [0003] As a molecular spectrum, Raman spectroscopy can reflect the structural information and property changes of biomolecules. Since the process of tumor formation must be accompanied by significant changes in the configuration, conformation and quantity of major biomolecules such as carbohydrates, lipids, proteins, and nucleic acids that constitute cells and tissues, these changes occur e...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/65
Inventor 李庆波王巍
Owner BEIHANG UNIV
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