Intelligent pressure guide wire based on flexible MEMS sensors and manufacturing method of sensors

Abstract

The invention provides an intelligent pressure guide wire based on flexible MEMS sensors and a manufacturing method of the sensors. The body of the pressure guide wire is of a solid structure, the guide wire is made to rotate in the circumference by controlling the head of the guide wire, and the guide wire can move forward in a blood vessel of a human body in cooperation with the axial feeding of the guide wire; the pressure sensors which are distributed on multiple points are arranged at the tail of the pressure guide wire and connected with internal leads, the sensors reach the head of the guide wire along the guide wire, a sensor lead electrode point is arranged on the head of the guide wire and connected with a controlling handle, and blood flow pressure signals measured by the pressure sensors are collected in real time. The pressure sensors are fully flexible and wrap the surface of the guide wire in a wind-around mode; the head of the guide wire is designed to be flat so that the head of the guide wire can be connected with an external torque sensor on the controlling handle and the feedback torque generated when the guide wire rotates can be measured in real time. The guide wire solves the problem of limitation existing in the manufacturing and measurement process of an existing pressure guide wire.

Description

technical field [0001] The invention relates to a pressure guide wire, which is an intelligent pressure guide wire based on a flexible MEMS sensor and a preparation method of the sensor for measuring blood flow pressure in coronary arteries in cardiovascular interventional treatment. Background technique [0002] In 1993, NicoPijls proposed a new index for calculating coronary blood flow through pressure measurement—Fractional Flow Reserve (FFR), which uses the measurement of the pressure at the proximal and distal ends of the coronary artery lesion area to calculate the diseased blood vessel. Actual blood flow, functional judgment of coronary stenosis on myocardial perfusion, can directly provide evidence of myocardial ischemia. A number of large-scale international studies such as COURAGE, FAME, DEFFER, and the FAMEII study newly announced at the 2012 European Cardiovascular Annual Meeting have established that FFR is the "gold standard" for evaluating coronary artery func...

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Problems solved by technology

[0006] In view of the defects in the prior art, the purpose of the present invention is to provide an intelligent pressure guide wire based on flexible MEMS sensors, which solves the limitations of the current pressure guide wire production and measurement

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