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Oral medicine for treating diabetic retinopathy

A technology for diabetic retina and drugs, applied in the field of plant materials, can solve the problems of many toxic side effects and high price

Inactive Publication Date: 2014-05-07
西安市第四医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Drugs currently on the market for the treatment of diabetic retinopathy mainly include chemical drugs such as calcium dobesilate and diframin. These drugs have many side effects after long-term use and are expensive.

Method used

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  • Oral medicine for treating diabetic retinopathy
  • Oral medicine for treating diabetic retinopathy
  • Oral medicine for treating diabetic retinopathy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Taking the production of 1000 pharmaceutical capsule products of the present invention as an example, the used Chinese medicine raw materials and auxiliary materials and their proportioning ratio are:

[0025]

[0026]

[0027] Its preparation method is as follows:

[0028] Add water to decoct the Qiwei such as Chushizi and Shengdi in the proportioning of the present invention twice, the first time for 2 hours, the second time for 1.5 hours, filter, combine the filtrates, concentrate to a relative density of 1.20~1.25 (measured at 70°C) , add ethanol to make the alcohol content reach 55%, let it stand for 24 hours, take the supernatant, recover the ethanol under reduced pressure until there is no alcohol smell, continue to concentrate into a thick paste, add medicinal starch, mix well, granulate, and pack into capsules , that is. Each grain weighs 0.4g, and each gram contains 5.525g of traditional Chinese medicine raw materials.

[0029] Taking the production of...

Embodiment 2

[0042] Taking the production of 1000 pharmaceutical capsule products of the present invention as an example, the used Chinese medicine raw materials and auxiliary materials and their proportioning ratio are:

[0043]

[0044] Its preparation process is identical with the preparation process of embodiment 1 capsule. Each grain weighs 0.4g, and each gram contains 5.525g of traditional Chinese medicine raw materials.

[0045] Taking the production of 1000 tablets of the pharmaceutical tablet product of the present invention as an example, the used Chinese medicine raw materials and auxiliary materials and their proportioning ratio are:

[0046]

[0047] Its preparation process is carried out according to the preparation process of the tablet of the present invention. Each piece weighs 0.4g, and each gram contains 5.525g of traditional Chinese medicine raw materials.

[0048] Taking the production of 1000g of the granule product of the present invention as an example, the ...

Embodiment 3

[0058] Taking the production of 1000 pharmaceutical capsule products of the present invention as an example, the used Chinese medicine raw materials and auxiliary materials and their proportioning ratio are:

[0059]

[0060] Its preparation process is identical with the preparation process of embodiment 1 capsule. Each grain weighs 0.4g, and each gram contains 5.525g of traditional Chinese medicine raw materials.

[0061] Taking the production of 1000 tablets of the pharmaceutical tablet product of the present invention as an example, the used Chinese medicine raw materials and auxiliary materials and their proportioning ratio are:

[0062]

[0063]

[0064] Its preparation process is carried out according to the preparation process of the tablet of the present invention. Each piece weighs 0.4g, and each gram contains 5.525g of traditional Chinese medicine raw materials.

[0065] Taking the production of 1000g of the granule product of the present invention as an exa...

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Abstract

The invention discloses an oral medicine for treating diabetic retinopathy which is prepared from the following traditional Chinese medicinal materials in parts by weight according to a conventional preparation method: 30-60 parts of Broussonetia papyrifera fruit 30-60 parts, 20-50 parts of Rehmannia glutinosa 20-50 parts, 20-40 parts of Spatholobus suberectus stem 20-40 parts, 10-25 parts of Panax quinquefolium 10-25 parts, 30-60 parts of Astragalus membranaceus 30-60 parts, 10-40 parts of Scrophularia ningpoensis 10-40 parts, and Pollen Typhae (Typha angustifolia and / or Typha orientalis) parts. Clinical trials show that the oral medicine of the invention has remarkable therapeutic effect on diabetic retinopathy. The oral medicine of the invention is remarkably superior to commercial medicines in overall therapeutic effect, traditional Chinese medicine (TCM) syndrome therapeutic effect, TCM syndrome scores and fundus hemorrhage area and other indicators in eye examination.

Description

technical field [0001] The invention belongs to the technical field of medical preparations containing raw materials or their reaction products with unknown structures, and specifically relates to materials derived from plants. Background technique [0002] Diabetic retinopathy (DR) is one of the most common and serious microvascular complications of diabetes and has become the leading cause of blindness in working-age populations in most developed countries. According to the latest report in 2010, China currently has more than 92.4 million diabetic (DM) patients, making it the largest country in the world with diabetes. With the rapid increase in the number of diabetic patients in my country and the increase in the number of patients with diabetes, the number of patients with diabetic complications will increase significantly. Among people over 20 years old in my country, the prevalence of diabetes in males and females is 10.6% and 8.8%, respectively, and the overall preva...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P9/10A61P3/10
Inventor 雷晓琴
Owner 西安市第四医院
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