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Absorbable skull screw and preparation method thereof

A screw and skull technology, applied in the field of absorbable skull screws and its preparation, can solve problems such as infection, interference with patients' magnetic images, allergies, etc., achieve broad medical application prospects, good mechanical and physical properties, and reduce the risk of infection

Inactive Publication Date: 2014-06-11
TIANJIN KANGLIER BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these skull screws are made of titanium alloy. Long-term implantation will cause corrosion and allergies. Therefore, a second removal operation is required, and there is a risk of infection. In addition, it will interfere with the patient's magnetic image and affect the patient's CT and MRI examination. result
[0006] In recent years, more fracture fixators made of absorbable materials have been used clinically and have achieved better internal fixation effects. However, the mechanical properties of these absorbable biodegradable fixators are weak, which limits their wide application.

Method used

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  • Absorbable skull screw and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] 1. Materials

[0030] The polylactic acid used in this example is poly-L-lactide (PLLA), purchased from Changchun Shengboma Biomaterials Co., Ltd., and its viscosity-average molecular weight is 800,000;

[0031] 2. Preparation process

[0032] Add poly L-lactide (PLLA) into the injection barrel of the injection device of the ZWK-760 screw horizontal automatic plastic injection molding machine, turn on the heating device, heat and plasticize the PLLA into a fluid state, and then inject it under the injection pressure of 170Mpa Down injection into the skull screw injection mold;

[0033] The mold clamping device clamps the injection mold under the mold clamping force of 760KN, and then cools the injection mold. After the plastic parts in the injection mold are cooled, the mold is opened, and the plastic parts are taken out to obtain absorbable skull screws. The thread sizes of absorbable skull screws are shown in Table 1.

[0034] 3. Performance measurement

[0035] 1...

Embodiment 2

[0049] The polylactic acid used in this example is poly DL-lactide (PDLLA), purchased from Changchun Shengboma Biomaterials Co., Ltd., and its viscosity-average molecular weight is 500,000;

[0050] Add poly DL-lactide (PDLLA) into the injection barrel of the injection device of the ZWK-760 screw horizontal automatic plastic injection molding machine, turn on the heating device, heat and plasticize the PDLLA into a fluid state, and then inject it under the injection pressure of 170Mpa Down injection into the skull screw injection mold;

[0051]The mold clamping device closes the injection mold under the mold clamping force of 760KN, and then cools the injection mold. After the plastic parts in the injection mold are cooled, the mold is opened, and the plastic parts are taken out to obtain absorbable skull screws. The thread size of the absorbable skull screw is shown in Table 1;

[0052] The absorbable skull screw prepared in this example has a bending strength of 82Mpa, a be...

Embodiment 3

[0054] The polylactic acid used in this example is poly D-lactide (PDLA), purchased from Changchun Shengboma Biomaterials Co., Ltd., and its viscosity-average molecular weight is 400,000;

[0055] Add poly D-lactide (PDLA) into the injection barrel of the injection device of the ZWK-760 screw horizontal automatic plastic injection molding machine, turn on the heating device, heat and plasticize the PDLA into a fluid state, and then inject it under the injection pressure of 170Mpa Down injection into the skull screw injection mold;

[0056] The mold clamping device closes the injection mold under the mold clamping force of 760KN, and then cools the injection mold. After the plastic parts in the injection mold are cooled, the mold is opened, and the plastic parts are taken out to obtain absorbable skull screws. The thread size of the absorbable skull screw is shown in Table 1;

[0057] The absorbable skull screw prepared in this example has a bending strength of 80Mpa, a bendin...

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Abstract

The invention discloses an absorbable skull screw and a preparation method thereof. The absorbable skull screw is prepared through injection molding of polylactide. The polylactide employed in the invention is biodegradable and bacteriostatic and has anti-mildew performance and high security; the prepared absorbable skull screw has excellent physical and mechanical properties, and when used for internal fixation, the skull screw can be absorbed by tissue without removal through secondary operation, thereby lowering down infection risks of the wound of a patient; compared with traditional stainless steel or titanium alloy products, the absorbable skull screw provided by the invention does not interfere in magnetic images and exerts no influence on CT and nuclear magnetic examination results, so the absorbable skull screw has good medical application prospects.

Description

technical field [0001] The invention relates to a medical device, in particular to an absorbable skull screw for internal fixation and a preparation method thereof. Background technique [0002] Polylactic acid (H-[OCHCH 3 CO]n-OH, PLA), also known as polylactide, belongs to the polyester family and is a polymer obtained by polymerization of lactic acid as the main raw material. Polylactic acid can be obtained by dehydration and polycondensation of lactic acid using a solvent under vacuum, or it can be obtained by first making lactic acid into a cyclic dimer lactide, and then performing ring-opening polycondensation. It can also be obtained by batch stirring reactor and twin-screw The extruder performs continuous melt polymerization. The raw material lactic acid can be fermented and produced by agricultural and sideline products. The source is sufficient and renewable. The whole production process is pollution-free, and the product can be biodegraded to realize the cycle i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/06
Inventor 安宗源甘澎兰成营
Owner TIANJIN KANGLIER BIOTECH