The invention discloses a special sampling box for medical health monitoring, which includes a heat preservation box, a water bag is arranged in the heat preservation box, a storage box, an arc-shaped hollow pipe, a clamping mechanism, and a collection pipe are arranged in the heat preservation box. The arc-shaped hollow pipe is fixed with an internal threaded pipe, and the internal threaded pipe is threadedly connected with the external threaded pipe. The external threaded pipe is fixed with a three-way valve, and the three-way valve is connected with the first connecting pipe. The heat preservation box is fixed with a lifting mechanism, a disinfection mechanism, a recovery box, and a tool box. Through the heat preservation box, water bag, and arc-shaped hollow tube, not only the storage box can be fixed, but also the shock absorption effect can be achieved to ensure the collection inside the storage box. The tube will not be damaged due to excessive shaking, and by injecting cooling liquid into the water bag, the internal environment of the insulation box and storage box can be kept at a low temperature, which further protects the organisms in the sample and prevents the sample from dying due to high temperature, resulting in collection failure ,waste time.