Novel application of catalpol

A new use, the technology of catalpol, applied in the field of traditional Chinese medicine, can solve the problems of lack of clinical data and statistics

Inactive Publication Date: 2014-06-18
玄振玉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine treatment is mostly compound decoction treatment or integrated traditional Chinese and Western medicine treatment, which is aimed at many individual cases and lacks a large amount of clinical data statistics

Method used

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  • Novel application of catalpol
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  • Novel application of catalpol

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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0011] In the following, the present invention will be further described in detail and completely in conjunction with embodiments.

[0012] 1 material

[0013] 1.1 Experimental animals

[0014] Clean grade Kunming mice, 18-25 grams.

[0015] 1.2 Drugs

[0016] Test drug: Catalpol (20g).

[0017] Control drugs: L-thyroid sodium, methimazole tablets.

[0018] 1.3 Reagent

[0019] Iodine [125I] Triiodothyronine (T3) Radioimmunoassay Kit; Iodine [125I] Thyroxine (T4) Radioimmunoassay Kit; Iodine [125I] Free Triiodothyronine (FT3) Radioimmunoassay Analysis kit; Iodine [125I] free thyroxine (FT4) radioimmunoassay kit.

[0020] 1.4 Instrument

[0021] JA5003A electronic balance; ECG-6511 electrocardiograph; CY-3 digital oxygen meter; SN-697 radioimmuno gamma counter; KK25E73TI Siemens refrigerator; Scanspeed mini centrifuge; DL-50RC cryogenic centrifuge.

[0022] 2 method

[0023] 2.1 Animal model preparation

[0024] The animals before the experiment adapt to the environment indoors for 2 days. Twe...

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Abstract

The invention discloses a novel application of catalpol. The novel application is an application of catalpol in preparation of drugs or healthcare food for treating hyperthyroidism or hyperthyroid heart disease related with hyperthyroidism. It has been proved by experiment results that catalpol can improve the appearance and behavior of hyperthyroidism mice, is tend to increase the weight of mice, can reduce the oxygen consumption and slow down the heart rate, has a prominent reducing effect on T3, FT3, and FT4, and has a prominent reducing effect on the whole heart weight index and left ventricle weight index.

Description

Technical field [0001] The invention relates to a new use of catalpol, in particular to the application of catalpol in the preparation of drugs or health foods for treating hyperthyroidism, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] Hyperthyroidism, abbreviated as "hyperthyroidism" or "hyperthyroidism", is an excess of thyroid hormone caused by various causes, enters the blood circulation, acts on the tissues and organs of the body, and causes the body to have high metabolism and increased neuropsychological excitability Syndrome is the main clinical syndrome. With the increase of social and work pressure and the acceleration of life rhythm, the incidence of hyperthyroidism has increased significantly. Epidemiological investigations have found that the male to female incidence ratio is 1:4-1:6, and it is more common in 20-40 years old. The disease is more common in women. The total incidence of hyperthyroidism in my country ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61P5/16A61P9/00A23L1/29A23L33/00
CPCA61K31/7048A23L1/29A23L33/10A61P5/14A61P5/16A61P9/00
Inventor 玄振玉
Owner 玄振玉
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