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A kind of pharmaceutical preparation for treating depression

A pharmaceutical preparation and technology for depression, which is applied in the field of pharmaceutical preparations for the treatment of depression, can solve the problems of easy relapse, narrow antidepressant spectrum, and large toxic and side effects

Inactive Publication Date: 2016-09-14
SHANDONG UNIV QILU HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] For the treatment of depression, Western medicine currently uses 5-hydroxytryptamine reuptake inhibitors, monoamine oxidase inhibitors, phenylpyrazine derivatives, 5-hydroxytryptamine-norepinephrine reuptake inhibitors, aminoketones, tricyclics, Seven types of antidepressants such as tetracycline pyrazine azepines, but most of the synthetic antidepressants have defects such as narrow antidepressant spectrum, large toxic and side effects, high drug price and easy relapse

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Example 1 Preparation of pharmaceutical preparations for the treatment of depression

[0013] The formula is: 25 grams of purslane, 15 grams of epimedium, 25 grams of polygala, 15 grams of tangerine peel, 25 grams of polygonatum, 15 grams of parsley, 25 grams of Sanqi, 25 grams of astragalus, 10 grams of vine 10 grams, Cnidium 10 grams, Corydalis 25 grams.

[0014] The preparation method is: take each raw material, mix, add 10 times the amount (weight multiple) of water, decoct for 3 hours, filter to obtain the filtrate, add 5 times the amount (weight multiple) of water to the medicinal residue, and decoct for 2 hours , filtered to obtain the filtrate, combined the two filtrates, concentrated under reduced pressure and dried to obtain the medicinal powder, and packed into capsules to make capsules (0.3 grams per capsule).

Embodiment 2

[0015] Example 2 Preparation of pharmaceutical preparations for the treatment of depression

[0016] The formula is: 20 grams of purslane, 20 grams of epimedium, 20 grams of polygala, 20 grams of orange peel, 20 grams of Polygonatum odoratum, 20 grams of parsley, 20 grams of Panax notoginseng, 30 grams of astragalus, 5 grams of broad tendon vine, rehmannia glutinosa 15 grams, Cnidium 5 grams, Corydalis 30 grams.

[0017] The preparation method is: take each raw material, mix, add 8 times the amount (weight multiple) of water, decoct for 2 hours, filter to obtain the filtrate, add 6 times the amount (weight multiple) of water to the medicinal residue, and decoct for 2 hours , filtered to obtain the filtrate, combined the two filtrates, concentrated under reduced pressure, dried to obtain the medicinal powder, packed into capsules to make capsules, and obtained.

Embodiment 3

[0018] Example 3 Preparation of pharmaceutical preparations for the treatment of depression

[0019] The formula is: 30 grams of purslane, 10 grams of epimedium, 30 grams of Polygala, 10 grams of tangerine peel, 30 grams of Polygonatum odoratum, 10 grams of parsley, 30 grams of Panax notoginseng, 20 grams of astragalus, 15 grams of vine 5 grams, Fructus Cnidii 15 grams, Corydalis 20 grams.

[0020] The preparation method is: take each raw material, mix, add 9 times the amount (weight multiple) of water, decoct for 2.5 hours, filter to obtain the filtrate, add 4 times the amount (weight multiple) of water to the medicinal residue, and decoct for 1 hour , filtered to obtain the filtrate, combined the two filtrates, concentrated under reduced pressure, dried to obtain the medicinal powder, packed into capsules to make capsules, and obtained.

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PUM

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Abstract

The invention discloses a pharmaceutical preparation for treating depression. The pharmaceutical preparation is prepared from the following crude drugs in parts by weight: 20-30 parts of herba portulacae, 10-20 parts of herba epimedii, 20-30 parts of polygala tenuifolia, 10-20 parts of pericarpium citri reticulatae, 20-30 parts of radix polygonati officinalis, 10-20 parts of ajowan, 20-30 parts of pseudo-ginseng, 20-30 parts of astragalus membranaceus, 5-15 parts of tinospora sinensis merr, 5-15 parts of rehmannia glutinosa, 5-15 parts of common cnidium fruits and 20-30 parts of corydalis sibirica. The preparation method comprises the following steps: mixing each crude drug; adding 8-10 times of water, and decocting for 2-3 hours; filtering to obtain filtrate; adding water to dregs, decocting for 1-2 hours, and filtering to obtain filtrate; merging the filtrate of twice, concentrating and drying into powder; enclosing into capsules to prepare the capsules. The pharmaceutical preparation for treating the depression disclosed by the invention is orally taken about 1g for three times a day in treatment, 15 days are taken as a course of treatment, and the depression can be cured by 2-3 courses of treatment in general.

Description

technical field [0001] The invention relates to a pharmaceutical preparation for treating depression. Background technique [0002] Depression is a common affective mental disorder. It is a disease characterized by persistent low mood or mood, lack of interest, slow thinking, anorexia, sexual dysfunction, sleep disturbance and other physical symptoms. It can be caused by various reasons, with significant and persistent depression as the main clinical feature, and the depression is not commensurate with the situation. In severe cases, suicidal thoughts and behaviors may appear. Most cases have a tendency to relapse, and most of each attack can be relieved, and some may have residual symptoms or become chronic. Traditional Chinese medicine believes that depression belongs to the category of depression syndrome, which is a kind of disease caused by emotional discomfort and qi stagnation. The main manifestations are depression, restlessness, flank pain, or irritability, crying...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8969A61K9/48A61P25/24
Inventor 王梦欣
Owner SHANDONG UNIV QILU HOSPITAL